Drugs / CNTX-6970
last change Jan 2026 re-read 3 minutes ago

CNTX-6970

Small molecule targets CCR2, CCR5 via inhibition

Developed for
osteoarthritis, knee
Investigated by
Centrexion Therapeutics · Maurizio Fava, MD

Trials 2

2018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 11 trial
Phase 1 NCT03787004 Aug 2017 → Aug 2018 chronic pain syndrome Centrexion Therapeutics Completed No outcome recorded
Phase 21 trial · 1 missed
Phase 2 NCT05025787 Oct 2021 → Jun 2024 osteoarthritis, knee Maurizio Fava, MD Completed Missed primary

Evidence & citations 6 cited values

Every value below carries the sentence it was read from. 3 sources stand behind the page.

FieldValueCited text
Known as CNTX-6970 ClinicalTrials.gov intervention name — accepted as the source's own label NCT05025787 ↗
1

NCT03787004 ↗

Action Inhibit “pharmacologic blockade of specific chemokine receptors with this compound” PMID 41468282 ↗ Jan 2026
Modality Small molecule “a small molecule” PMID 41468282 ↗ Jan 2026
Route Oral “Oral dose CNTX-6970” NCT03787004 ↗
Target CCR2 “cytokine chemokine receptor type 2 (CCR2)” PMID 41468282 ↗ Jan 2026
Target CCR5 “CCR5 antagonist” PMID 41468282 ↗ Jan 2026