Drugs / taprenepag isopropyl
last change Sep 2011 re-read 2 minutes ago

taprenepag isopropyl

also known as PF-04217329

Small molecule targets PTGER2 via activation

Developed for
ocular hypertension · open-angle glaucoma
Investigated by
Pfizer

Trials 2 · a red edge is where a trial was stopped

20082009201020112012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 2 NCT00934089 Jan → Jun 2010 ocular hypertension, open-angle glaucoma Pfizer Completed No outcome recorded
Phase 2 NCT00572455 Dec 2007 → Jun 2009 ocular hypertension, open-angle glaucoma Pfizer Completed No outcome recorded

Evidence & citations 6 cited values

Every value below carries the sentence it was read from. 4 sources stand behind the page.

FieldValueCited text
Known as taprenepag isopropyl “A phase 2, randomized, dose-response trial of taprenepag isopropyl (PF-04217329)” PMID 21851167 Sep 2011
Known as PF-04217329 ClinicalTrials.gov intervention name — accepted as the source's own label NCT00934089
1

NCT00572455

Action Activate “a selective EP(2) receptor agonist” PMID 21851167 Sep 2011
1

“Prostanoid EP2 receptor agonist” CHEMBL2105692

Modality Small molecule CHEMBL2105692
Route Topical “administered as a topical ophthalmic solution” PMID 21851167 Sep 2011
Target PTGER2 “Prostanoid EP2 receptor agonist” CHEMBL2105692