Drugs / MK8245
last change Jul 2016 re-read 3 minutes ago

MK8245

Small molecule targets SCD via inhibition

Developed for
type 2 diabetes mellitus
Investigated by
Merck Sharp & Dohme LLC

Trials 3

2009201020112012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 12 trials · 1 missed
Phase 1 NCT00972322 Aug 2009 → Jan 2010 type 2 diabetes mellitus Merck Sharp & Dohme LLC Completed Missed primary
Phase 1 NCT00790556 Oct 2008 → Sep 2009 type 2 diabetes mellitus Merck Sharp & Dohme LLC Completed No outcome recorded
Phase 21 trial
Phase 2 NCT00846391 Dec 2008 → Aug 2009 type 2 diabetes mellitus Merck Sharp & Dohme LLC Terminated No outcome recorded Stop: Enrollment

Evidence & citations 4 cited values

Every value below carries the sentence it was read from. 5 sources stand behind the page.

FieldValueCited text
Known as MK8245 ClinicalTrials.gov intervention name — accepted as the source's own label NCT00790556 ↗
2

NCT00846391 ↗

NCT00972322 ↗

Action Inhibit “liver-specific SCD-1 inhibitor, MK8245” PMID 27392483 ↗ Jul 2016
Modality Small molecule — CHEMBL1938870 ↗
Target SCD “liver-specific SCD-1 inhibitor, MK8245” PMID 27392483 ↗ Jul 2016