Drugs / PGE2
last change Oct 2025 re-read 3 minutes ago

PGE2

also known as Cervidil · Propess · prostaglandin E2
Developed for
cervix disorder · preterm premature rupture of the membranes
Investigated by
Danish Headache Center · Guangzhou Women and Children's Medical Center

Trials 2

200720082009201020112012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 41 trial
Phase 4 NCT04780269 Dec 2023 → Dec 2024 — Guangzhou Women and Children's Medical Center Suspended No outcome recorded
Phase not applicable1 trial
— NCT00374530 Aug 2006 → ? migraine disorder Danish Headache Center Completed No outcome recorded
Comparator or background therapy5 trials
Phase 2 NCT02856724 Background Aug → Oct 2016 — Zeynep Kamil Maternity and Pediatric Research and Training Hospital Completed No outcome recorded
Phase 4 NCT00355966 Comparator Aug 2006 → Sep 2008 preterm premature rupture of the membranes Nilratan Sircar Medical College Completed No outcome recorded
Phase 4 NCT00355303 Comparator Aug 2006 → May 2013 preterm premature rupture of the membranes Nilratan Sircar Medical College Completed No outcome recorded
— NCT07261332 Comparator May → Oct 2025 obstetric disorder, preterm premature rupture of the membranes Laiba Qamar Completed No outcome recorded
— NCT06591247 Comparator Aug 2024 → Dec 2027 expected cervix disorder, pregnancy disorder Meir Medical Center Recruiting No outcome recorded

Press releases naming this drug 1 release

DateIssuerRelease
2020-04-15 Khondrion BV Khondrion highlights potential role of inflammatory lipid modulator prostaglandin E2 in COVID-19 disease khondrion.com ↗

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 7 sources stand behind the page.

FieldValueCited text
Known as PGE2 ClinicalTrials.gov intervention name — accepted as the source's own label NCT02856724 ↗
6

NCT00374530 ↗

NCT07261332 ↗

NCT04780269 ↗

NCT06591247 ↗

NCT00355966 ↗

NCT00355303 ↗

Known as Cervidil “A PGE2 vaginal pessary (Cervidil) will be inserted for 12-24 hours” NCT06591247 ↗
Known as Propess “10 mg PGE2 vaginal ovul(Propess)” NCT02856724 ↗
Known as prostaglandin E2 “since its main component is prostaglandin E2 (PGE2).” NCT02856724 ↗
Route Other “PGE2 gel will be applied in poaterior fornix at six hrly interval with maximum of 2 doses” NCT00355303 ↗