Drugs / BEROTERKIB ANHYDROUS
BEROTERKIB ANHYDROUS
also known as
ASTX029 · ASTX-029 MONOHYDRATE · AT-35029 · AT-35029 MONOHYDRATE · BEROTERKIB · Beroterkib monohydrate
Trials 3 · a red edge is where a trial was stopped
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 11 trial | ||||||
| Phase 1 | NCT04466514 | Jul → Oct 2020 | — | Astex Pharmaceuticals, Inc. | Completed | No outcome recorded |
| Phase 1/22 trials | ||||||
| Phase 1/2 | NCT06284460 | Jan → Dec 2025 | myelodysplastic syndrome, myeloproliferative neoplasm | M.D. Anderson Cancer Center | Withdrawn | No outcome recorded |
| Phase 1/2 | NCT03520075 | May 2018 → Aug 2024 | cancer | Taiho Oncology, Inc. | Completed | No outcome recorded |
Evidence & citations 10 cited values
Every value below carries the sentence it was read from. 4 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | BEROTERKIB ANHYDROUS | ChEMBL registry synonym — accepted as the source's own label CHEMBL4847260 ↗ |
| Known as | ASTX-029 MONOHYDRATE | ChEMBL registry synonym — accepted as the source's own label CHEMBL4847260 ↗ |
| Known as | ASTX029 | ClinicalTrials.gov intervention name — accepted as the source's own label NCT03520075 ↗ |
| Known as | AT-35029 | ChEMBL registry synonym — accepted as the source's own label CHEMBL4847260 ↗ |
| Known as | AT-35029 MONOHYDRATE | ChEMBL registry synonym — accepted as the source's own label CHEMBL4847260 ↗ |
| Known as | BEROTERKIB | ChEMBL registry synonym — accepted as the source's own label CHEMBL4847260 ↗ |
| Known as | Beroterkib monohydrate | ChEMBL registry synonym — accepted as the source's own label CHEMBL4847260 ↗ |
| Action | Inhibit | “ASTX029 is a synthetic small molecule inhibitor of extracellular signal-regulated kinases (ERKs) 1/2.” NCT03520075 ↗ |
| Modality | Small molecule | “ASTX029 is a synthetic small molecule inhibitor of extracellular signal-regulated kinases (ERKs) 1/2.” NCT03520075 ↗ |
| Route | Oral | “ASTX029 administered orally” NCT03520075 ↗ |