Drugs / BGB-43395
last change 4 days ago re-read 2 minutes ago

BGB-43395

targets CDK4 via inhibition

Developed for
hormone receptor-positive breast cancer · metastatic neoplasm · neoplasm · non-small cell lung carcinoma · Her2-receptor negative breast cancer
Investigated by
BeOne Medicines · BeiGene

Trials 7 · a red edge is where a trial was stopped

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 16 trials
Phase 1 NCT07226349 Dec 2025 → Nov 2028 expected neoplasm BeOne Medicines Recruiting No outcome recorded
Phase 1 NCT06756932 Feb 2025 → Jul 2027 expected hormone receptor-positive breast cancer BeOne Medicines Recruiting No outcome recorded
Phase 1 NCT06761898 Jan → May 2025 BeiGene Completed No outcome recorded
Phase 1 NCT06253195 Apr 2024 → Apr 2026 hormone receptor-positive breast cancer, metastatic neoplasm BeOne Medicines Completed No outcome recorded
Phase 1 NCT06257264 Mar 2024 → Aug 2026 overdue endometrial cancer, gastric cancer, gastroesophageal cancer, hormone receptor-positive breast cancer +5 BeiGene Active not recruiting No outcome recorded
Phase 1 NCT06120283 Dec 2023 → Nov 2028 expected hormone receptor-positive breast cancer, non-small cell lung carcinoma BeOne Medicines Recruiting No outcome recorded
Phase 31 trial
Phase 3 NCT07492641 May 2026 → Apr 2029 expected hormone receptor-positive breast cancer BeOne Medicines Recruiting No outcome recorded

Evidence & citations 4 cited values

Every value below carries the sentence it was read from. 7 sources stand behind the page.

FieldValueCited text
Known as BGB-43395 ClinicalTrials.gov intervention name — accepted as the source's own label NCT06253195
6

NCT07226349

NCT06756932

NCT06761898

NCT07492641

NCT06120283

NCT06257264

Action Inhibit “a selective cyclin-dependent kinase 4 (CDK4) inhibitor” NCT06120283
Route Oral “Planned doses administered orally.” NCT06120283
Target CDK4 “a selective cyclin-dependent kinase 4 (CDK4) inhibitor” NCT06120283