Drugs / APRINOCARSEN
last change Jun 2002 re-read 3 minutes ago

APRINOCARSEN

also known as LY900003 · ISIS 3521 · Pkc-alpha

Antisense oligonucleotide targets PRKCA

Developed for
non-small cell lung carcinoma
Investigated by
Eli Lilly and Company

Trials 2

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PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 21 trial
Phase 2 NCT00042679 Jun 2002 → ? non-small cell lung carcinoma Eli Lilly and Company Completed No outcome recorded
Phase 31 trial
Phase 3 NCT00034268 Mar 2002 → ? non-small cell lung carcinoma Eli Lilly and Company Completed No outcome recorded

News releases announcing trial results or a regulatory action · 1

DateIssuerRelease
2002-05-20 Ionis Pharmaceuticals Results New Affinitac(TM) Data in Non-Small Cell Lung Cancer Presented at ASCO ionis.com ↗
The new findings on Affinitac, presented at ASCO on Sunday, May 19, are from ongoing, Phase II clinical trials.

All press releases naming this drug 1 release

DateIssuerRelease

Evidence & citations 6 cited values

Every value below carries the sentence it was read from. 3 sources stand behind the page.

FieldValueCited text
Known as APRINOCARSEN ChEMBL registry synonym — accepted as the source's own label CHEMBL2108287 ↗
Known as ISIS 3521 “A Phase 2 Trial of Antisense Nucleotide to PKC-Alpha (LY900003, ISIS 3521) Plus Gemcitabine and Carboplatin in Patients With Advanced, Previously Untreated Non-Small Cell Lung Cancer.” NCT00042679 ↗
Known as LY900003 ClinicalTrials.gov intervention name — accepted as the source's own label NCT00042679 ↗
1

NCT00034268 ↗

Known as Pkc-alpha ChEMBL registry synonym — accepted as the source's own label CHEMBL2108287 ↗
Modality Antisense oligonucleotide “Antisense Nucleotide to PKC-Alpha” NCT00042679 ↗
Target PRKCA “Antisense Nucleotide to PKC-Alpha” NCT00042679 ↗