Drugs / EDP167
last change Aug 2026 re-read 3 minutes ago

EDP167

Small interfering RNA (siRNA) targets ANGPTL3 via inhibition

Developed for
homozygous familial hypercholesterolemia
Investigated by
Eddingpharm (Zhuhai) Co., Ltd.

Trials 2

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 11 trial
Phase 1 NCT07412080 Jul → Dec 2025 — Eddingpharm (Zhuhai) Co., Ltd. Completed No outcome recorded
Phase 21 trial
Phase 2 NCT07489209 Feb → Oct 2026 expected homozygous familial hypercholesterolemia Eddingpharm (Zhuhai) Co., Ltd. Recruiting No outcome recorded

News releases announcing trial results or a regulatory action · 1

DateIssuerRelease
2026-08-21 Eddingpharm (Zhuhai) Co., Ltd. Results 亿腾嘉和多款产品研究成果即将公布 创新研发实力再上台阶 eddingpharm.com ↗
EDP167的FIH研究显示整体安全性和耐受性良好,初步展现了全面改善致动脉粥样硬化血脂谱的能力,提示EDP167有潜力成为新一代的降脂药物。

All press releases naming this drug 1 release

DateIssuerRelease

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 2 sources stand behind the page.

FieldValueCited text
Known as EDP167 ClinicalTrials.gov intervention name — accepted as the source's own label NCT07412080 ↗
1

NCT07489209 ↗

Action Inhibit “EDP167 is a novel GalNAc-conjugated siRNA therapeutic that selectively silences hepatic ANGPTL3 mRNA expression” NCT07412080 ↗
Modality Small interfering RNA (siRNA) “EDP167 is a double-stranded small interfering RNA (siRNA) drug targeting ANGPTL3” NCT07412080 ↗
Route Subcutaneous “following a single subcutaneous injection of EDP167” NCT07412080 ↗
Target ANGPTL3 “EDP167 is a double-stranded small interfering RNA (siRNA) drug targeting ANGPTL3” NCT07412080 ↗