Drugs / ATECEGATRAN METOXIL
last change Jun 2009 re-read 9 days ago

ATECEGATRAN METOXIL

Small molecule targets F2 via inhibition

Developed for
persistent atrial fibrillation · atrial fibrillation
Investigated by
AstraZeneca

Trials 7

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 14 trials
Phase 1 NCT00904800 May → Jun 2009 — AstraZeneca Completed No outcome recorded
Phase 1 NCT00878618 Apr → May 2009 — AstraZeneca Completed No outcome recorded
Phase 1 NCT00812643 Jan → Feb 2009 — AstraZeneca Completed No outcome recorded
Phase 1 NCT00812344 Dec 2008 → Mar 2009 — AstraZeneca Completed No outcome recorded
Phase 23 trials
Phase 2 NCT00645853 Oct 2007 → May 2009 persistent atrial fibrillation AstraZeneca Completed No outcome recorded
Phase 2 NCT00623779 Oct 2007 → Oct 2008 persistent atrial fibrillation AstraZeneca Completed No outcome recorded
Phase 2 NCT00684307 Feb 2007 → Jun 2008 atrial fibrillation AstraZeneca Completed No outcome recorded

Evidence & citations 8 cited values

Every value below carries the sentence it was read from. 8 sources stand behind the page.

FieldValueCited text
Known as ATECEGATRAN METOXIL ChEMBL registry synonym — accepted as the source's own label CHEMBL4297593 ↗
Known as Atecegatran fexenetil ChEMBL registry synonym — accepted as the source's own label CHEMBL4297593 ↗
Known as Atecegatran metoxilo ChEMBL registry synonym — accepted as the source's own label CHEMBL4297593 ↗
Known as AZD0837 ClinicalTrials.gov intervention name — accepted as the source's own label NCT00623779 ↗
6

NCT00904800 ↗

NCT00812344 ↗

NCT00645853 ↗

NCT00812643 ↗

NCT00684307 ↗

NCT00878618 ↗

Action Inhibit “oral direct thrombin inhibitor” NCT00645853 ↗
1

“Thrombin inhibitor” CHEMBL4297593 ↗

Modality Small molecule — CHEMBL4297593 ↗
Route Oral “Oral Direct Thrombin Inhibitor, AZD0837” NCT00623779 ↗
Target F2 “Thrombin inhibitor” CHEMBL4297593 ↗