Drugs / hEGFRvIII-CD3
last change Aug 2026 re-read 3 minutes ago

hEGFRvIII-CD3

Protein / enzyme biologic targets EGFR

Developed for
glioblastoma
Investigated by
Adaptin Bio · Mustafa Khasraw, MBChB, MD, FRCP, FRACP

Trials 1

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1 NCT04903795 Aug 2026 → Dec 2027 expected glioblastoma Mustafa Khasraw, MBChB, MD, FRCP, FRACP Not yet recruiting No outcome recorded

Evidence & citations 4 cited values

Every value below carries the sentence it was read from. 1 source stands behind the page.

FieldValueCited text
Known as hEGFRvIII-CD3 ClinicalTrials.gov intervention name — accepted as the source's own label NCT04903795 ↗
Modality Protein / enzyme biologic “Bispecific T cell engager possessing one effector binding arm specific for the epsilon subunit of CD3” NCT04903795 ↗
Route Intravenous “continuously infused intravenously (IV)” NCT04903795 ↗
Target EGFR “target-binding arm is directed against the hEGFRvIII epitope” NCT04903795 ↗