Drugs / PSMA ADC
last change Mar 2015 re-read 3 minutes ago

PSMA ADC

Other / unclassified

Developed for
prostate cancer · glioblastoma
Investigated by
Progenics Pharmaceuticals, Inc. · Heinrich Elinzano, MD · Rhode Island Hospital · University of Texas

Trials 5

2009201020112012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 12 trials
Phase 1 NCT01414296 Jan 2009 → Sep 2013 prostate cancer Progenics Pharmaceuticals, Inc. Completed No outcome recorded
Phase 1 NCT01414283 Oct 2008 → Apr 2013 prostate cancer Progenics Pharmaceuticals, Inc. Completed No outcome recorded
Phase 23 trials
Phase 2 NCT02020135 Oct 2013 → Feb 2015 prostate cancer Progenics Pharmaceuticals, Inc. Completed No outcome recorded
Phase 2 NCT01856933 May 2013 → Nov 2014 gliosarcoma Heinrich Elinzano, MD Completed No outcome recorded
Phase 2 NCT01695044 Sep 2012 → Oct 2014 prostate cancer Progenics Pharmaceuticals, Inc. Completed No outcome recorded

Evidence & citations 4 cited values

Every value below carries the sentence it was read from. 5 sources stand behind the page.

FieldValueCited text
Known as PSMA ADC ClinicalTrials.gov intervention name — accepted as the source's own label NCT01414283 ↗
4

NCT01856933 ↗

NCT01414296 ↗

NCT02020135 ↗

NCT01695044 ↗

Action Deplete “Following binding and internalization of PSMA ADC, the cytotoxic component of PSMA ADC will be released and destroy the neovasculature that supports tumor growth.” NCT01856933 ↗
Modality Other / unclassified “Prostate Specific Membrane Antigen Antibody Drug Conjugate (PSMA ADC)” NCT01695044 ↗
Route Intravenous “PSMA ADC administered IV” NCT01414283 ↗