Drugs / TELRATOLIMOD
last change Oct 2020 re-read 3 minutes ago

TELRATOLIMOD

also known as 3M-052 · MEDI9197

Small molecule targets TLR7, TLR8 via activation

Developed for
primary cutaneous T-cell lymphoma
Investigated by
MedImmune LLC

Trials 1

201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1 NCT02556463 Nov 2015 → Oct 2018 primary cutaneous T-cell lymphoma MedImmune LLC Terminated No outcome recorded Stop: Business

Evidence & citations 8 cited values

Every value below carries the sentence it was read from. 3 sources stand behind the page.

FieldValueCited text
Known as TELRATOLIMOD ChEMBL registry synonym — accepted as the source's own label CHEMBL4297631 ↗
Known as 3M-052 ChEMBL registry synonym — accepted as the source's own label CHEMBL4297631 ↗
Known as MEDI9197 ClinicalTrials.gov intervention name — accepted as the source's own label NCT02556463 ↗
Action Activate “MEDI9197 is an intratumorally administered toll-like receptor 7 and 8 agonist” PMID 33037117 ↗ Oct 2020
2

“Toll-like receptor 7 agonist” CHEMBL4297631 ↗

“Toll-like receptor 8 agonist” CHEMBL4297631 ↗

Modality Small molecule — CHEMBL4297631 ↗
Route Other “Administered intratumorally” NCT02556463 ↗
Target TLR7 “Toll-like receptor 7 agonist” CHEMBL4297631 ↗
Target TLR8 “Toll-like receptor 8 agonist” CHEMBL4297631 ↗