Drugs / Pf p52(-)/p36(-) GAP
last change Sep 2013 re-read 3 minutes ago

Pf p52(-)/p36(-) GAP

also known as p52-/p36- GAP vaccine

targets GTF2H4, H3C9P

Developed for
malaria
Investigated by
Seattle Children's Hospital

Trials 1

201020112012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1/2 NCT01024686 Mar 2010 → Jun 2011 malaria Seattle Children's Hospital Terminated No outcome recorded

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 2 sources stand behind the page.

FieldValueCited text
Known as Pf p52(-)/p36(-) GAP “A first generation Plasmodium falciparum GAP (Pf p52(-)/p36(-) GAP) was previously generated by deletion of two pre-erythrocytic stage-expressed genes (P52 and P36) in the NF54 strain.” PMID 24029408 ↗ Sep 2013
Known as p52-/p36- GAP vaccine “p52-/p36- GAP Vaccine: Administered by five bites from GAP-infected Anopheles mosquito” NCT01024686 ↗
Route Other “via infected Anopheles mosquito bite” PMID 24029408 ↗ Sep 2013
Target P36 “deletion of two pre-erythrocytic stage-expressed genes (P52 and P36)” PMID 24029408 ↗ Sep 2013
Target P52 “deletion of two pre-erythrocytic stage-expressed genes (P52 and P36)” PMID 24029408 ↗ Sep 2013