Drugs / Liafensine
Liafensine
Trials 6 · a red edge is where a trial was stopped
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 12 trials | ||||||
| Phase 1 | NCT01396252 | Sep 2011 → May 2012 | depressive disorder | Bristol-Myers Squibb | Completed | No outcome recorded |
| Phase 1 | NCT00892840 | May 2009 → Nov 2010 | depressive disorder | Bristol-Myers Squibb | Completed | No outcome recorded |
| Phase 24 trials | ||||||
| Phase 2 | NCT05113771 | Jun 2022 → Feb 2024 | — | Denovo Biopharma LLC | Completed | No outcome recorded |
| Phase 2 | NCT01361555 | Aug 2011 → Oct 2013 | major depressive disorder | Bristol-Myers Squibb | Terminated | No outcome recorded |
| Phase 2 | NCT01369095 | Jul 2011 → May 2013 | depressive disorder | Bristol-Myers Squibb | Completed | No outcome recorded |
| Phase 2 | NCT01309945 | Apr 2011 → Jan 2013 | depressive disorder | Bristol-Myers Squibb | Completed | No outcome recorded |
Also used as a comparator or background therapy in 1 trial
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 1 | NCT00964912 Comparator | Jul 2008 → Apr 2009 | depressive disorder | Bristol-Myers Squibb | Completed | No outcome recorded |
Evidence & citations 6 cited values
Every value below carries the sentence it was read from. 9 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | Liafensine | ClinicalTrials.gov intervention name — accepted as the source's own label NCT05113771 ↗ |
| Known as | BMS-820836 | ClinicalTrials.gov intervention name — accepted as the source's own label NCT01361555 ↗ |
| Known as | Liafensina | ChEMBL registry synonym — accepted as the source's own label CHEMBL2364614 ↗ |
| Action | Inhibit | “Liafensine, a triple reuptake inhibitor, may become a new precision medicine for treatment-resistant depression (TRD), a major unmet medical need.” PMID 40928787 ↗ Dec 2025 |
| Modality | Small molecule | — CHEMBL2364614 ↗ |
| Route | Oral | “Oral Solution, Oral” NCT00892840 ↗ |