Drugs / Decidual Stromal Cells
Decidual Stromal Cells
Trials 6 · a red edge is where a trial was stopped
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 1/23 trials | ||||||
| Phase 1/2 | NCT02175303 | Dec 2013 → Dec 2017 | acute lung injury, disease related to hematopoietic stem cell transplant | Karolinska Institutet | Unknown | No outcome recorded |
| Phase 1/2 | NCT02172963 | Nov 2011 → Dec 2013 | hemorrhagic cystitis | Karolinska Institutet | Completed | No outcome recorded |
| Phase 1/2 | NCT02172937 | Jan 2011 → Dec 2016 | acute graft versus host disease | Karolinska Institutet | Unknown | No outcome recorded |
| Phase 22 trials | ||||||
| Phase 2 | NCT05132166 | Dec 2021 → Apr 2026 overdue | graft versus host disease | University Health Network, Toronto | Active not recruiting | No outcome recorded |
| Phase 2 | NCT04926194 | Mar → Jun 2021 | chronic graft versus host disease, myelodysplastic/myeloproliferative neoplasm | University Health Network, Toronto | Completed | No outcome recorded |
| Phase not applicable1 trial | ||||||
| — | NCT04451291 | Sep 2020 → Nov 2023 | COVID-19, acute respiratory distress syndrome | University Health Network, Toronto | Completed | No outcome recorded |
Also used as a comparator or background therapy in 1 trial
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 2 | NCT02174536 Comparator | Mar 2014 → Dec 2016 | disease related to hematopoietic stem cell transplant, endometrial stromal nodule, hemorrhagic cystitis | Karolinska Institutet | Unknown | No outcome recorded |
Evidence & citations 6 cited values
Every value below carries the sentence it was read from. 8 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | Decidual Stromal Cells | “Decidual stromal cells from placenta will be infused intravenously at approximately 1x10\^6 cells/kg at one or more occasions at weekly intervals.” NCT02175303 ↗6“Intravenous injection with placenta derived Decidual Stromal Cells.” NCT02172963 ↗ |
| Known as | decidua stromal cells | “maternal stromal cells from the fetal membrane, so-called decidua stromal cells (DSCs), are more immunosuppressive than other sources of stromal cells” PMID 31173898 ↗ Jun 2019 |
| Known as | DSC | “Decidual Stromal Cells (DSC)” NCT04451291 ↗ |
| Known as | DSCs | “maternal stromal cells from the fetal membrane, so-called decidua stromal cells (DSCs), are more immunosuppressive than other sources of stromal cells” PMID 31173898 ↗ Jun 2019 |
| Modality | Cell therapy | “decidual stromal cell therapy” NCT02172937 ↗ |
| Route | Intravenous | “Intravenous injection” NCT02172963 ↗ |