eugenol
Trials 6 · a red edge is where a trial was stopped
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 1/21 trial | ||||||
| Phase 1/2 | NCT07475364 | May → Dec 2026 expected | dental pulp necrosis | University of Faisalabad | Not yet recruiting | No outcome recorded |
| Phase 22 trials | ||||||
| Phase 2 | NCT06823544 | Feb → Jul 2025 overdue | alveolar periostitis | HITEC-Institute of Medical Sciences | Not yet recruiting | No outcome recorded |
| Phase 2 | NCT03650036 | Jun 2018 → May 2019 | dental pulp necrosis | Federal University of Piaui | Completed | No outcome recorded |
| Phase 2/31 trial | ||||||
| Phase 2/3 | NCT05862441 | Jan 2018 → Dec 2019 | common wart | University of Antwerp | Completed | No outcome recorded |
| Phase 32 trials | ||||||
| Phase 3 | NCT07475663 | Nov 2025 → Feb 2026 | epicondylitis, osteoarthritis, knee, patellofemoral pain syndrome, tenosynovitis of foot and ankle | Taisho Pharmaceutical Indonesia | Completed | No outcome recorded |
| Phase 3 | NCT06366568 | Feb → Mar 2024 | — | Colgate Palmolive | Completed | No outcome recorded |
Also used as a comparator or background therapy in 1 trial
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| — | NCT05615272 Comparator | Oct 2022 → Mar 2024 | alveolar periostitis | University of Dublin, Trinity College | Unknown | No outcome recorded |
Evidence & citations 10 cited values
Every value below carries the sentence it was read from. 8 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | eugenol | “AV2 is a combination of FDA GRAS-label approved organic compounds (natural essential oils: carvone, eugenol, geraniol, and nerolidol) that is postulated to be able to prevent...” NCT05862441 ↗6“Placement of CTZ antibiotic paste (chloramphenicol, tetracycline, zinc oxide mixed with eugenol) in the pulp chamber after irrigation with 3% sodium hypochlorite, followed by...” NCT07475364 ↗ “CTZ paste is composed of 62.5 mg of chloramphenicol, 62.5 mg of tetracycline and 125 mg of zinc oxide and manipulated with 0.1ml of eugenol in a sterile glass plate with...” NCT03650036 ↗ “The gel contains 0.5% Piroxicam as the anti-inflammatory agent, combined with three counterirritants: Methyl Salicylate, Menthol, and Eugenol.” NCT07475663 ↗ “Alveogyl is an intraalveolar sedative, obtundent dressing, which contains the active ingredient eugenol.” NCT05615272 ↗ |
| Known as | 4-allylcatechol 2-methyl ether | ChEMBL registry synonym — accepted as the source's own label CHEMBL42710 ↗ |
| Known as | Bioxeda | ChEMBL registry synonym — accepted as the source's own label CHEMBL42710 ↗ |
| Known as | Caryophillic acid | ChEMBL registry synonym — accepted as the source's own label CHEMBL42710 ↗ |
| Known as | Dentogum | ChEMBL registry synonym — accepted as the source's own label CHEMBL42710 ↗ |
| Known as | FEMA NO. 2467 | ChEMBL registry synonym — accepted as the source's own label CHEMBL42710 ↗ |
| Known as | NSC-209525 | ChEMBL registry synonym — accepted as the source's own label CHEMBL42710 ↗ |
| Known as | NSC-8895 | ChEMBL registry synonym — accepted as the source's own label CHEMBL42710 ↗ |
| Modality | Small molecule | “AV2 is a combination of FDA GRAS-label approved organic compounds (natural essential oils: carvone, eugenol, geraniol, and nerolidol) that is postulated to be able to prevent...” NCT05862441 ↗ |
| Route | Topical | “applying it directly to the painful area.” NCT07475663 ↗ |