Drugs / SRN001
last change Jan 2026 re-read 3 minutes ago

SRN001

Small interfering RNA (siRNA) targets AREG via inhibition

Investigated by
siRNAgen Therapeutics Inc.

Trials 2

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1 NCT07407543 Jan → Oct 2026 expected idiopathic pulmonary fibrosis siRNAgen Therapeutics Inc. Recruiting No outcome recorded
Phase 1 NCT05984992 Sep 2023 → Mar 2024 idiopathic pulmonary fibrosis siRNAgen Therapeutics Inc. Completed No outcome recorded

Evidence & citations 4 cited values

Every value below carries the sentence it was read from. 2 sources stand behind the page.

FieldValueCited text
Known as SRN001 ClinicalTrials.gov intervention name — accepted as the source's own label NCT07407543 ↗
1

NCT05984992 ↗

Action Inhibit “SRN-001 is designed to downregulate generating amphiregulin by RNA interference (RNAi).” NCT05984992 ↗
Modality Small interfering RNA (siRNA) “novel small interfering RNA (siRNA) drug” NCT05984992 ↗
Target AREG “Amphiregulin (AREG) is a growth factor involved in fibroblast proliferation and myofibroblast transformation which is the hallmark of fibrosis in lung and kidney tissues. AREG...” NCT07407543 ↗