Drugs / Coenzyme A
last change May 2021 re-read 2 minutes ago

Coenzyme A

also known as CoA · Coash

Small molecule

Developed for
hyperlipoproteinemia · castration-resistant prostate carcinoma
Investigated by
Zhejiang University · Affiliated Hospital of Jiangnan University · Jiangnan University

Trials 4 · a red edge is where a trial was stopped

20112012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1/21 trial
Phase 1/2 NCT04839055 Mar → Apr 2021 castration-resistant prostate carcinoma Jiangnan University Unknown No outcome recorded
Phase 2/31 trial
Phase 2/3 NCT01928342 Mar 2012 → Sep 2013 hyperlipoproteinemia Zhejiang University Unknown No outcome recorded
Phase 32 trials
Phase 3 NCT01878227 Jul 2010 → May 2011 hyperlipoproteinemia Zhejiang University Completed No outcome recorded
Phase 3 NCT01811082 Jul 2010 → May 2011 hyperlipoproteinemia Zhejiang University Completed No outcome recorded
Also used as a comparator or background therapy in 1 trial
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 2 NCT01645046 Comparator Oct 2008 → Jun 2009 hyperlipoproteinemia Zhejiang University Completed No outcome recorded

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 7 sources stand behind the page.

FieldValueCited text
Known as Coenzyme A ClinicalTrials.gov intervention name — accepted as the source's own label NCT01928342
4

NCT01811082

NCT04839055

NCT01878227

NCT01645046

Known as CoA “Coenzyme A (CoA) is a ubiquitous essential cofactor that plays a central role in the metabolism of carboxylic acids, including short- and long-chain fatty acids, as well as...” NCT01811082
3

“Coenzyme A (CoA) functions as an acyl group carrier and assists in transferring fatty acids from the cytoplasm to mitochondria.” NCT01878227

“a new hypolipidemic agent, coenzyme A (CoA) to stable statin therapy” PMID 24382338 Jan 2014

“Coenzyme A (CoA)” NCT04839055

Known as Coash ChEMBL registry synonym — accepted as the source's own label CHEMBL1213327
Modality Small molecule CHEMBL1213327
Route Oral “high dose CoA orally” NCT01645046