Drugs / anti-OX40
last change Jun 2023 re-read 2 minutes ago

anti-OX40

Monoclonal antibody

Developed for
cancer of unknown primary site · metastatic melanoma · metastatic prostate carcinoma
Investigated by
Providence Health & Services · MedImmune LLC

Trials 3 · a red edge is where a trial was stopped

200420052006200720082009201020112012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 12 trials
Phase 1 NCT01303705 Oct 2010 → Jul 2016 metastatic prostate carcinoma Providence Health & Services Completed No outcome recorded
Phase 1 NCT01644968 Nov 2003 → May 2009 cancer of unknown primary site Providence Health & Services Completed No outcome recorded
Phase 21 trial
Phase 2 NCT01416844 Sep 2012 metastatic melanoma Providence Health & Services Withdrawn No outcome recorded

Press releases naming this drug 1 release

DateIssuerRelease
2023-06-27 Sanofi Press Release: Positive topline Phase 2b data in atopic dermatitis support amlitelimab as a potential first and best-in-class novel investigational anti-OX40-ligand monoclonal antibody sanofi.com

Evidence & citations 4 cited values

Every value below carries the sentence it was read from. 4 sources stand behind the page.

FieldValueCited text
Known as anti-OX40 ClinicalTrials.gov intervention name — accepted as the source's own label NCT01416844
2

NCT01303705

NCT01644968

Action Activate “a mouse monoclonal antibody (mAb) that agonizes human OX40 signaling” PMID 24177180 Oct 2013
Modality Monoclonal antibody Monoclonal Antibody to OX40” NCT01303705
Route Intravenous “Anti-OX40 will be administered intravenously” NCT01303705