Drugs / somapacitan
last change Feb 2026 re-read 2 minutes ago

somapacitan

Protein / enzyme biologic targets GHR via activation

Developed for
pituitary deficiency · fetal growth restriction · Noonan syndrome · Turner syndrome · gastroparesis · isolated short stature
Investigated by
Novo Nordisk A/S · Mayo Clinic

Regulatory milestones approvals, filings & regulatory actions · 4 recorded

MilestoneJurisdictionBrandIndicationDateSentence it was read from
Label expansions (2) US (FDA) SOGROYA 2023-04-28 – 2026-02-27 fda.gov
Approved EU (EMA) Sogroya 2021-03-31 europa.eu
Approved US (FDA) SOGROYA 2020-08-28 fda.gov

Trials 17 · a red edge is where a trial was stopped

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 01 trial
Phase 0 NCT06803589 Oct 2024 → Oct 2027 expected gastroparesis Mayo Clinic Recruiting No outcome recorded
Phase 17 trials
Phase 1 NCT03905850 Mar → Jul 2019 pituitary deficiency Novo Nordisk A/S Completed No outcome recorded
Phase 1 NCT03212131 Aug 2017 → Mar 2018 pituitary deficiency Novo Nordisk A/S Completed No outcome recorded
Phase 1 NCT03186495 Jun 2017 → May 2018 Novo Nordisk A/S Completed No outcome recorded
Phase 1 NCT02962440 Nov 2016 → Jan 2017 Novo Nordisk A/S Completed No outcome recorded
Phase 1 NCT01973244 Dec 2013 → Nov 2014 Novo Nordisk A/S Completed No outcome recorded
Phase 1 NCT01706783 Oct 2012 → Nov 2013 Novo Nordisk A/S Completed No outcome recorded
Phase 1 NCT01514500 Jan 2012 → Mar 2013 pituitary deficiency Novo Nordisk A/S Completed No outcome recorded
Phase 22 trials
Phase 2 NCT03878446 Jul 2019 → May 2021 overdue fetal growth restriction Novo Nordisk A/S Active not recruiting No outcome recorded
Phase 2 NCT02616562 Mar 2016 → Sep 2024 pituitary deficiency Novo Nordisk A/S Completed No outcome recorded
Phase 37 trials
Phase 3 NCT05723835 Feb 2023 → Jun 2024 overdue Noonan syndrome, Turner syndrome, fetal growth restriction Novo Nordisk A/S Active not recruiting No outcome recorded
Phase 3 NCT05330325 Aug 2022 → Aug 2024 overdue Noonan syndrome, Turner syndrome, isolated short stature Novo Nordisk A/S Active not recruiting No outcome recorded
Phase 3 NCT04970654 Jul 2021 → Nov 2023 pituitary deficiency Novo Nordisk A/S Completed No outcome recorded
Phase 3 NCT03811535 May 2019 → Nov 2021 pituitary deficiency Novo Nordisk A/S Completed No outcome recorded
Phase 3 NCT03075644 Mar 2017 → Oct 2018 pituitary deficiency Novo Nordisk A/S Completed No outcome recorded
Phase 3 NCT02382939 Feb 2015 → Jan 2016 pituitary deficiency Novo Nordisk A/S Completed No outcome recorded
Phase 3 NCT02229851 Oct 2014 → Apr 2017 pituitary deficiency Novo Nordisk A/S Completed No outcome recorded

Evidence & citations 10 cited values

Every value below carries the sentence it was read from. 19 sources stand behind the page.

FieldValueCited text
Known as somapacitan ClinicalTrials.gov intervention name — accepted as the source's own label NCT02616562
15

NCT04970654

NCT02229851

NCT03878446

NCT03811535

NCT03075644

NCT01706783

NCT03905850

NCT05330325

NCT03186495

NCT02382939

NCT02962440

NCT01514500

NCT05723835

NCT03212131

NCT01973244

Known as NN-8640 ChEMBL registry synonym — accepted as the source's own label CHEMBL3707290
Known as NNC0195-0092 “A Trial to Evaluate the Safety of Once Weekly Dosing of Somapacitan (NNC0195-0092) and Daily Norditropin® FlexPro® for 52 Weeks in Previously Human Growth Hormone Treated...” NCT03075644
Known as Sogroya ChEMBL registry synonym — accepted as the source's own label CHEMBL3707290
Known as Sogroya (Somapacitan-beco injections) Sogroya (Somapacitan-beco injections)NCT06803589
Known as somapacitan-beco “Subjects will receive somapacitan-beco (Sogroya®) administered as a subcutaneous injection once weekly for 12 weeks.” NCT06803589
Action Activate “Growth hormone receptor agonist” CHEMBL3707290
Modality Protein / enzyme biologic “Somapacitan, a long-acting growth hormone (GH) derivative” PMID 29671202 Jan 2019
Route Subcutaneous “A single dose administered subcutaneously (s.c., under the skin)” NCT01973244
Target GHR “Growth hormone receptor agonist” CHEMBL3707290