Drugs / Chimeric Antigen Receptor T-Cell Therapy

Trials 5

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 14 trials · 1 met primary
Phase 1 NCT05052528 Sep 2021 → May 2027 expected relapsed/refractory diffuse large B-cell lymphoma University of California, Davis Recruiting No outcome recorded
Phase 1 NCT04007029 Oct 2019 → Aug 2026 overdue chronic lymphocytic leukemia/small lymphocytic lymphoma, follicular lymphoma, mantle cell lymphoma, primary mediastinal large B-cell lymphoma Jonsson Comprehensive Cancer Center Active not recruiting No outcome recorded
Phase 1 NCT03696030 Aug 2018 → Jan 2027 expected HER2 positive breast carcinoma, malignant leptomeningeal tumor, metastatic malignant neoplasm in the brain City of Hope Medical Center Active not recruiting No outcome recorded
Phase 1 NCT03233854 Sep 2017 → Jun 2023 overdue B-cell acute lymphoblastic leukemia Stanford University Active not recruiting Met primary
Phase 1/21 trial
Phase 1/2 NCT03277729 Dec 2017 → Mar 2024 overdue Richter transformation, central nervous system non-hodgkin lymphoma, chronic lymphocytic leukemia/small lymphocytic lymphoma, diffuse large B-cell lymphoma +4 Fred Hutchinson Cancer Center Active not recruiting No outcome recorded
Comparator or background therapy3 trials
Phase 0 NCT05800405 Background Jul 2023 → Jan 2027 expected diffuse large B-cell lymphoma City of Hope Medical Center Recruiting No outcome recorded
Phase 2 NCT06854159 Background Aug 2025 → Oct 2028 expected diffuse large B-cell lymphoma University of California, Davis Recruiting No outcome recorded
Phase 2 NCT05202782 Background Mar 2022 → Oct 2026 expected T-cell/histiocyte rich large B cell lymphoma, diffuse large B-cell lymphoma with chronic inflammation, high grade B-cell lymphoma, high-grade B-cell lymphoma double-hit/triple-hit +4 Northwestern University Active not recruiting No outcome recorded

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 8 sources stand behind the page.

FieldValueCited text
Known as Chimeric Antigen Receptor T-Cell Therapy ClinicalTrials.gov intervention name — accepted as the source's own label NCT03233854 ↗
7

NCT06854159 ↗

NCT05052528 ↗

NCT03696030 ↗

NCT05800405 ↗

NCT04007029 ↗

NCT05202782 ↗

NCT03277729 ↗

Action Deplete “may recognize and kill tumor cells” NCT03696030 ↗
Modality Cell therapy “CD19/CD22 chimeric antigen receptor (CAR) T cells” NCT03233854 ↗
Route Intravenous “Given CD19/CD22 CAR T cells IV” NCT03233854 ↗
Target CD19 “infusion of chimeric antigen receptor T cells targeting CD19” NCT05052528 ↗