Drugs / TGFBR2 KO CAR27/IL-15 NK cells
last change Sep 2025 re-read 2 minutes ago

TGFBR2 KO CAR27/IL-15 NK cells

Cell therapy targets TGFBR2 via inhibition

Developed for
myeloid neoplasm
Investigated by
M.D. Anderson Cancer Center

Trials 1 · a red edge is where a trial was stopped

202620272028
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1/2 NCT06930651 Sep 2025 → May 2028 expected myeloid neoplasm M.D. Anderson Cancer Center Recruiting No outcome recorded

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 1 source stands behind the page.

FieldValueCited text
Known as TGFBR2 KO CAR27/IL-15 NK cells ClinicalTrials.gov intervention name — accepted as the source's own label NCT06930651
Action Inhibit “TGFBR2 KO” NCT06930651
Modality Cell therapy “one-time infusion of the CAR.70/IL15-transduced/TGFBR2KO CB-NK cells” NCT06930651
Route Other “Given by Infusion” NCT06930651
Target TGFBR2 TGFBR2 KO” NCT06930651