Drugs / Tocotrienols
Trials 1
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 2/31 trial | ||||||
| Phase 2/3 | NCT03807037 | Dec 2018 → Dec 2021 | atrial fibrillation | Monash University Malaysia | Completed | No outcome recorded |
| Comparator or background therapy3 trials | ||||||
| Phase 1/2 | NCT03705845 Comparator | Mar 2019 → Dec 2024 overdue | obesity disorder | Texas Tech University Health Sciences Center | Active not recruiting | No outcome recorded |
| Phase 1/2 | NCT02058420 Comparator | Feb 2014 → Oct 2022 | osteoporosis | Texas Tech University Health Sciences Center | Completed | No outcome recorded |
| Phase 2 | NCT04704063 Comparator | Jan 2021 → Aug 2023 | fatty liver disease | Yuen Kah Hay | Completed | No outcome recorded |
Evidence & citations 6 cited values
Every value below carries the sentence it was read from. 5 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | tocotrienols | “Mixed tocotrienols (derived from palm oil) to be orally administered at 200mg (1 capsule) twice daily, to achieve dosage of 400mg/day” NCT03807037 ↗3“annatto-extracted tocotrienols (TT) with antioxidant capability” PMID 32152169 ↗ Mar 2020 |
| Known as | Tocovid | “The aim of this study is to determine whether a potent antioxidative and anti-inflammatory agent, Tocovid, a tocotrienol-rich capsule, could reduce the incidence of POAF and...” PMID 34819126 ↗ Nov 2021 |
| Known as | Vitamin E | “Tocotrienols / Vitamin E” NCT04704063 ↗ |
| Action | Inhibit | “In view of emerging evidence on the HMG-CoA reductase inhibitory role in the incidence of AF and established inhibitory properties of tocotrienols, we postulate that...” NCT03807037 ↗ |
| Route | Oral | “to be orally administered at 200mg (1 capsule) twice daily” NCT03807037 ↗ |
| Target | HMGCR | “In view of emerging evidence on the HMG-CoA reductase inhibitory role in the incidence of AF and established inhibitory properties of tocotrienols, we postulate that...” NCT03807037 ↗ |