Drugs / Neisseria lactamica

Trials 3

PhaseRegistry idDatesIndicationSponsorStatusOutcome
— NCT04665791 Mar → Oct 2021 meningococcal meningitis Center for Vaccine Development - Mali Completed No outcome recorded
— NCT03549325 Mar 2017 → Dec 2021 meningococcal meningitis University Hospital Southampton NHS Foundation Trust Terminated No outcome recorded Stop: Enrollment
— NCT02249598 Jul → Nov 2013 — Sheffield Teaching Hospitals NHS Foundation Trust Completed No outcome recorded

Evidence & citations 7 cited values

Every value below carries the sentence it was read from. 4 sources stand behind the page.

FieldValueCited text
Known as Neisseria lactamica “inoculating adult volunteers with Neisseria lactamica, a harmless 'cousin' of N. meningitidis, possibly prevents N. meningitidis carriage.” NCT02249598 ↗
2

NCT04665791 ↗

NCT03549325 ↗

Known as LyoNlac “Nasally administered lyophilized Nlac (LyoNlac) might interrupt carriage and transmission of Nmen in sub-Saharan settings without requirement of a cold chain” PMID 41574175 ↗ Jan 2026
Known as N. lactamica “Previously, researchers have given nose drops containing N. lactamica to over 400 volunteers” NCT04665791 ↗
Known as Nlac “Nasally administered lyophilized Nlac (LyoNlac) might interrupt carriage and transmission of Nmen in sub-Saharan settings without requirement of a cold chain” PMID 41574175 ↗ Jan 2026
1

“N. lactamica (Nlac) has been shown to be safe to use in human challenge experiments.” NCT03549325 ↗

Known as Y92-1009 “reconstituted, lyophilized Nlac strain Y92-1009 (LyoNlac)” PMID 41574175 ↗ Jan 2026
Modality Other / unclassified “N.lactamica bacteria” NCT02249598 ↗
Route Intranasal “It will involve placing droplets of N.lactamica bacteria into the nose of half our group of volunteers” NCT02249598 ↗