Drugs / PX-478
last change May 2010 re-read 3 minutes ago

PX-478

Protein / enzyme biologic targets HIF1A via inhibition

Developed for
cancer · lymphoma
Investigated by
Cascadian Therapeutics Inc.

Trials 1

20082009201020112012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1 NCT00522652 Aug 2007 → May 2010 cancer, lymphoma Cascadian Therapeutics Inc. Completed No outcome recorded

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 3 sources stand behind the page.

FieldValueCited text
Known as PX-478 ClinicalTrials.gov intervention name — accepted as the source's own label NCT00522652 ↗
Action Inhibit “PX-478, an inhibitor of hypoxia-inducible factor-1alpha” PMID 18729192 ↗ Nov 2008
Modality Protein / enzyme biologic — CHEMBL4117516 ↗
Route Oral “Oral formulation” NCT00522652 ↗
Target HIF1A “PX-478, an inhibitor of hypoxia-inducible factor-1alpha” PMID 18729192 ↗ Nov 2008