Drugs / OSAVAMPATOR
last change Aug 2025 re-read 2 minutes ago

OSAVAMPATOR

also known as NBI-1065845 · TAK-653

Small molecule

Developed for
major depressive disorder · depressive disorder
Investigated by
Neurocrine Biosciences · Takeda · Millennium Pharmaceuticals, Inc.

Trials 9 · a red edge is where a trial was stopped

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 12 trials
Phase 1 NCT03792672 Feb → May 2019 Neurocrine Biosciences Completed No outcome recorded
Phase 1 NCT02561156 Aug 2015 → Sep 2017 depressive disorder Neurocrine Biosciences Completed No outcome recorded
Phase 22 trials
Phase 2 NCT05203341 Feb 2022 → Jan 2024 major depressive disorder Neurocrine Biosciences Completed No outcome recorded
Phase 2 NCT03312894 Feb 2018 → Feb 2019 Millennium Pharmaceuticals, Inc. Withdrawn No outcome recorded
Phase 35 trials
Phase 3 NCT07196501 Aug 2025 → Jul 2028 expected major depressive disorder Neurocrine Biosciences Recruiting No outcome recorded
Phase 3 NCT06963021 May 2025 → Jul 2027 expected major depressive disorder Neurocrine Biosciences Recruiting No outcome recorded
Phase 3 NCT06966401 Apr 2025 → May 2029 expected major depressive disorder Neurocrine Biosciences Recruiting No outcome recorded
Phase 3 NCT06911112 Mar 2025 → Jul 2027 expected major depressive disorder Neurocrine Biosciences Recruiting No outcome recorded
Phase 3 NCT06786624 Jan 2025 → Jul 2027 expected major depressive disorder Neurocrine Biosciences Recruiting No outcome recorded

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 10 sources stand behind the page.

FieldValueCited text
Known as OSAVAMPATOR ChEMBL registry synonym — accepted as the source's own label CHEMBL4594403
Known as NBI-1065845 ClinicalTrials.gov intervention name — accepted as the source's own label NCT05203341
5

NCT06966401

NCT06911112

NCT06786624

NCT07196501

NCT06963021

Known as TAK-653 ClinicalTrials.gov intervention name — accepted as the source's own label NCT03312894
2

NCT02561156

NCT03792672

Modality Small molecule CHEMBL4594403
Route Oral “TAK-653 0.3 mg, tablet, orally, once on Day 1” NCT02561156