Drugs / KB004
last change Sep 2021 re-read 3 minutes ago

KB004

Monoclonal antibody targets EPHA3

Developed for
glioblastoma · myelodysplastic syndrome · myelofibrosis
Investigated by
Humanigen, Inc. · Olivia Newton-John Cancer Research Institute

Trials 2

20112012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 11 trial
Phase 1 NCT03374943 Dec 2017 → Jan 2021 glioblastoma Olivia Newton-John Cancer Research Institute Completed No outcome recorded
Phase 1/21 trial
Phase 1/2 NCT01211691 Sep 2010 → Jul 2016 myelodysplastic syndrome, myelofibrosis Humanigen, Inc. Suspended No outcome recorded

Evidence & citations 4 cited values

Every value below carries the sentence it was read from. 3 sources stand behind the page.

FieldValueCited text
Known as KB004 ClinicalTrials.gov intervention name — accepted as the source's own label NCT01211691 ↗
1

NCT03374943 ↗

Modality Monoclonal antibody “anti-EphA3 monoclonal antibody KB004” NCT01211691 ↗
Route Intravenous “KB004 was administered by intravenous infusion on days 1, 8, and 15 of each 21-day cycle.” PMID 27736729 ↗ Sep 2016
Target EPHA3 “anti-EphA3 monoclonal antibody KB004” NCT01211691 ↗