Drugs / berberine ursodeoxycholate
berberine ursodeoxycholate
also known as
HTD1801 · BUDCA · HTD1801 capsules · Ursodeoxycholate de berberine · Ursodeoxycholato de berberina
Trials 10 · a red edge is where a trial was stopped
Also used as a comparator or background therapy in 2 trials
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 11 trial | ||||||
| Phase 1 | NCT03099603 Comparator | Mar → Jul 2017 | primary sclerosing cholangitis | HighTide Biopharma Pty Ltd | Completed | No outcome recorded |
| Phase 21 trial | ||||||
| Phase 2 | NCT03333928 Comparator | Feb 2018 → Apr 2020 | primary sclerosing cholangitis | HighTide Biopharma Pty Ltd | Completed | No outcome recorded |
Evidence & citations 8 cited values
Every value below carries the sentence it was read from. 14 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | berberine ursodeoxycholate | “Here we report on a prospective, randomised, double-blind, placebo-controlled trial of two doses of HTD1801 (berberine ursodeoxycholate, an ionic salt of berberine and...” PMID 34535644 ↗ Sep 20212“Pharmacokinetics and pharmacodynamics of HTD1801 (berberine ursodeoxycholate, BUDCA) in patients with hyperlipidemia.” PMID 33183320 ↗ Nov 2020 “Berberine ursodeoxycholate (HTD1801) is an ionic salt of berberine and ursodeoxycholic acid with” PMID 36327436 ↗ Aug 2022 |
| Known as | BUDCA | “Pharmacokinetics and pharmacodynamics of HTD1801 (berberine ursodeoxycholate,
BUDCA) in patients with hyperlipidemia.” PMID 33183320 ↗ Nov 20201“HTD1801 (BUDCA) 250 mg tablets. Dose 1000 mg twice daily with food for 12 weeks.” NCT04604652 ↗ |
| Known as | HTD1801 | “Here we report on a prospective, randomised, double-blind, placebo-controlled trial of two doses of HTD1801 (berberine ursodeoxycholate, an ionic salt of berberine and...” PMID 34535644 ↗ Sep 202111“Berberine ursodeoxycholate (HTD1801) is an ionic salt of berberine and ursodeoxycholic acid with” PMID 36327436 ↗ Aug 2022 |
| Known as | HTD1801 capsules | “HTD1801 capsules” NCT05623189 ↗ |
| Known as | Ursodeoxycholate de berberine | ChEMBL registry synonym — accepted as the source's own label CHEMBL5314422 ↗ |
| Known as | Ursodeoxycholato de berberina | ChEMBL registry synonym — accepted as the source's own label CHEMBL5314422 ↗ |
| Modality | Small molecule | “A small molecular compound for the treatment of primary sclerosing cholangitis” NCT03099603 ↗ |
| Route | Oral | “administered orally” NCT06350890 ↗ |