Drugs / ESTRADIOL VALERATE
ESTRADIOL VALERATE
also known as
Progynova · .beta.-estradiol 17-valerate · Climaval · Deladumone · Delestrogen · Estradiol 17-valerate · Estradiol valerate component of ditate-ds · Estradiol valerate component of natazia · +6 more
Small molecule targets ESR1 via activation
Trials 2
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 11 trial | ||||||
| Phase 1 | NCT06704516 | Jan → Aug 2025 overdue | metabolic dysfunction-associated steatotic liver disease | University of Oxford | Recruiting | No outcome recorded |
| Phase not applicable1 trial | ||||||
| — | NCT06067217 | Sep 2023 → Aug 2024 | — | Department of Medical Services Ministry of Public Health of Thailand | Unknown | No outcome recorded |
| Comparator or background therapy2 trials | ||||||
| Phase 2 | NCT03166189 Background | Dec 2017 → Mar 2019 | Asherman syndrome, female infertility of uterine origin | D.O. Ott Research Institute of Obstetrics, Gynecology, and Reproductology | Completed | No outcome recorded |
| — | NCT02148393 Comparator | May 2014 → Feb 2017 | infertility disorder, ovarian hyperstimulation syndrome | University Hospital Brussels | Completed | No outcome recorded |
Press releases naming this drug 2 releases
| Date | Issuer | Release |
|---|---|---|
| 2025-12-18 | Advanz Pharma | ADVANZ PHARMA Acquires Territory Rights to Progynova® and Cyclo-Progynova® in Selected Countries in EMEA and Global Rights to Ilomedin® advanzpharma.com ↗ |
| 2023-05-01 | Xiromed LLC | Xiromed LLC Launches Estradiol Valerate Injection, USP xiromed.com ↗ |
Evidence & citations 19 cited values
Every value below carries the sentence it was read from. 6 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | ESTRADIOL VALERATE | ChEMBL registry synonym — accepted as the source's own label CHEMBL1511 ↗ |
| Known as | .beta.-estradiol 17-valerate | ChEMBL registry synonym — accepted as the source's own label CHEMBL1511 ↗ |
| Known as | Climaval | ChEMBL registry synonym — accepted as the source's own label CHEMBL1511 ↗ |
| Known as | Deladumone | ChEMBL registry synonym — accepted as the source's own label CHEMBL1511 ↗ |
| Known as | Delestrogen | ChEMBL registry synonym — accepted as the source's own label CHEMBL1511 ↗ |
| Known as | Estradiol 17-valerate | ChEMBL registry synonym — accepted as the source's own label CHEMBL1511 ↗ |
| Known as | Estradiol valerate component of ditate-ds | ChEMBL registry synonym — accepted as the source's own label CHEMBL1511 ↗ |
| Known as | Estradiol valerate component of natazia | ChEMBL registry synonym — accepted as the source's own label CHEMBL1511 ↗ |
| Known as | Femtab | ChEMBL registry synonym — accepted as the source's own label CHEMBL1511 ↗ |
| Known as | NSC-17590 | ChEMBL registry synonym — accepted as the source's own label CHEMBL1511 ↗ |
| Known as | Progynon depot | ChEMBL registry synonym — accepted as the source's own label CHEMBL1511 ↗ |
| Known as | Progynon-depot-10 | ChEMBL registry synonym — accepted as the source's own label CHEMBL1511 ↗ |
| Known as | Progynova | “Brands of HRT include oestrogel, Evorel, Lenzetto, Estradot, Progynova (this list is not exhaustive)” NCT06704516 ↗3“4 mg Progynova (Bayer Pharma, Germany) daily on menstrual cycle day 5-25” NCT03166189 ↗ |
| Known as | Valerate d'estradiol | ChEMBL registry synonym — accepted as the source's own label CHEMBL1511 ↗ |
| Known as | Valerato de estradiol | ChEMBL registry synonym — accepted as the source's own label CHEMBL1511 ↗ |
| Action | Activate | “Estrogen receptor alpha agonist” CHEMBL1511 ↗ |
| Modality | Small molecule | — CHEMBL1511 ↗ |
| Route | Oral | “plus oral estradiol 2 mg two times a day” PMID 32964939 ↗ Dec 2020 |
| Target | ESR1 | “Estrogen receptor alpha agonist” CHEMBL1511 ↗ |