Drugs / iC9-CAR19 cells
last change Sep 2025 re-read 3 minutes ago

iC9-CAR19 cells

Cell therapy targets CD19 via depletion

Developed for
acute lymphoblastic leukemia · immunoproliferative disorder
Investigated by
Bellicum Pharmaceuticals · UNC Lineberger Comprehensive Cancer Center · The Leukemia and Lymphoma Society

Trials 2

2012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 11 trial
Phase 1 NCT03016377 Mar 2012 → Sep 2025 overdue acute lymphoblastic leukemia, immunoproliferative disorder UNC Lineberger Comprehensive Cancer Center Active not recruiting No outcome recorded
Phase not stated1 trial
— NCT03594162 — acute lymphoblastic leukemia, immunoproliferative disorder UNC Lineberger Comprehensive Cancer Center No longer available No outcome recorded

Evidence & citations 4 cited values

Every value below carries the sentence it was read from. 2 sources stand behind the page.

FieldValueCited text
Known as iC9-CAR19 cells ClinicalTrials.gov intervention name — accepted as the source's own label NCT03016377 ↗
1

NCT03594162 ↗

Action Deplete “These CD19 chimeric (combination) receptor-activated T cells kill some of the tumor” NCT03016377 ↗
Modality Cell therapy “autologous T lymphocyte chimeric antigen receptor cells” NCT03016377 ↗
Target CD19 “CAR-T cells targeting the CD19 antigen” NCT03016377 ↗