Drugs / MK-4166
last change Dec 2020 re-read 2 minutes ago

MK-4166

Monoclonal antibody

Developed for
cancer · glioblastoma
Investigated by
Bristol-Myers Squibb · Merck Sharp & Dohme LLC · Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

Trials 2 · a red edge is where a trial was stopped

2015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1 NCT03707457 Mar → Nov 2019 glioblastoma Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins Terminated No outcome recorded
Phase 1 NCT02132754 Jun 2014 → Jul 2019 cancer Merck Sharp & Dohme LLC Completed No outcome recorded

Evidence & citations 4 cited values

Every value below carries the sentence it was read from. 3 sources stand behind the page.

FieldValueCited text
Known as MK-4166 ClinicalTrials.gov intervention name — accepted as the source's own label NCT03707457
1

NCT02132754

Action Activate “humanized IgG1 agonist mAb targeting glucocorticoid-induced TNF receptor (GITR)” PMID 33355238 Dec 2020
Modality Monoclonal antibody “humanized IgG1 agonist mAb” PMID 33355238 Dec 2020
Route Intravenous “MK-4166 IV” NCT02132754