Drugs / XKH001
last change Apr 2026 re-read 3 minutes ago

XKH001

Monoclonal antibody targets IL25 via inhibition

Developed for
asthma · atopic eczema · chronic obstructive pulmonary disease
Investigated by
Zhejiang Kanova Biopharmaceutical Co., LTD

Trials 1

202420252026
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 11 trial
Phase 1 NCT07070297 Dec 2023 → Oct 2024 asthma Zhejiang Kanova Biopharmaceutical Co., LTD Completed No outcome recorded
Comparator or background therapy4 trials
Phase 1 NCT05128409 Comparator Mar 2023 → Oct 2024 — Beijing Kanova Biopharmaceutical Co., LTD Unknown No outcome recorded
Phase 1/2 NCT05991661 Comparator May 2023 → Feb 2024 asthma Beijing Kanova Biopharmaceutical Co., LTD Completed No outcome recorded
Phase 2 NCT07519499 Comparator Apr 2026 → Dec 2027 expected chronic obstructive pulmonary disease Zhejiang Kanova Biopharmaceutical Co., LTD Not yet recruiting No outcome recorded
Phase 2 NCT07054736 Comparator Aug → Oct 2025 overdue atopic eczema Zhejiang Kanova Biopharmaceutical Co., LTD Not yet recruiting No outcome recorded

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 6 sources stand behind the page.

FieldValueCited text
Known as XKH001 ClinicalTrials.gov intervention name — accepted as the source's own label NCT07070297 ↗
4

NCT05991661 ↗

NCT05128409 ↗

NCT07054736 ↗

NCT07519499 ↗

Action Inhibit “XKH001 specifically blocks interleukin-25 from binding to its receptors.” NCT05128409 ↗
Modality Monoclonal antibody “XKH001is a recombinant humanized monoclonal IgG1 antibody for subcutaneous injection.” NCT05128409 ↗
Route Subcutaneous “subcutaneous injection” NCT05128409 ↗
Target IL25 “XKH001 is a recombinant humanized IgG1 monoclonal antibody against IL-25 for the treatment of type 2 inflammatory diseases.” PMID 39815604 ↗ Jan 2025