Drugs / Cosopt

Regulatory milestones approvals, filings & regulatory actions · 1 recorded

MilestoneJurisdictionBrandIndicationDateSentence it was read from
Approved US (FDA) COSOPT 1998-04-07 fda.gov

Trials 1 · a red edge is where a trial was stopped

today
US approved 1998
NCT03257813 · Ph 3
199819992000200120022003200420052006200720082009201020112012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 3 NCT03257813 Apr 2016 → Mar 2017 ocular hypertension, open-angle glaucoma Laboratorios Sophia S.A de C.V. Completed No outcome recorded
Also used as a comparator or background therapy in 13 trials
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 11 trial
Phase 1 NCT03966365 Comparator May → Aug 2019 glaucoma Laboratorios Sophia S.A de C.V. Completed No outcome recorded
Phase 22 trials
Phase 2 NCT06177678 Comparator Feb → Sep 2024 ocular hypertension, open-angle glaucoma Kukje Pharma Unknown No outcome recorded
Phase 2 NCT01814514 Comparator Jan 2011 → Mar 2013 hypertensive disorder Zahra Rabbani Khah Unknown No outcome recorded
Phase 2/31 trial
Phase 2/3 NCT03034772 Comparator Feb 2017 → Feb 2019 wet macular degeneration Wills Eye Completed No outcome recorded
Phase 33 trials
Phase 3 NCT07617532 Comparator Jun 2026 → Mar 2028 expected ocular hypertension, open-angle glaucoma Ache Laboratorios Farmaceuticos S.A. Not yet recruiting No outcome recorded
Phase 3 NCT05973318 Comparator Apr 2017 → Sep 2018 open-angle glaucoma Jadran Galenski laboratorij d.d. Completed No outcome recorded
Phase 3 NCT00767481 Comparator Oct 2008 → Feb 2009 glaucoma, ocular hypertension Alcon Research Terminated No outcome recorded
Phase 44 trials
Phase 4 NCT00761995 Comparator Feb 2009 → Jul 2010 ocular hypertension, open-angle glaucoma Alcon Research Completed No outcome recorded
Phase 4 NCT00796198 Comparator Dec 2008 → Jun 2009 glaucoma University of Turin, Italy Unknown No outcome recorded
Phase 4 NCT00379834 Comparator Sep 2006 → Apr 2008 glaucoma West Virginia University Completed No outcome recorded
Phase 4 NCT00822055 Comparator May 2005 → Nov 2006 ocular hypertension, open-angle glaucoma Allergan Completed No outcome recorded
Phase not applicable2 trials
NCT01257698 Comparator Feb 2010 → Jun 2013 macular holes, retinal detachment Mid Atlantic Retina Completed No outcome recorded
NCT00804115 Comparator Aug 2000 → Sep 2007 exfoliation syndrome, ocular hypertension The New York Eye & Ear Infirmary Unknown No outcome recorded

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 14 sources stand behind the page.

FieldValueCited text
Known as Cosopt ClinicalTrials.gov intervention name — accepted as the source's own label NCT00804115
7

NCT05973318

NCT07617532

NCT06177678

NCT00796198

NCT00761995

NCT00379834

NCT00767481

Known as Dorzolamide-timolol “topical brimonidine-timolol BID or dorzolamide-timolol BID as monotherapy” PMID 19476406 Jul 2009
2

Dorzolamide-timolol topical drops” NCT01257698

NCT03034772

Known as Krytantek Ofteno ClinicalTrials.gov intervention name — accepted as the source's own label NCT03257813
1

NCT03966365

Known as Timolol-trusopt ClinicalTrials.gov intervention name — accepted as the source's own label NCT01814514
Route Topical topical eye drop” NCT00761995