Drugs / UNASNEMAB
last change Apr 2025 re-read 3 minutes ago

UNASNEMAB

also known as MT-3921 · rH116A3

Monoclonal antibody targets RGMA via inhibition

Developed for
spinal cord injury · tropical spastic paraparesis
Investigated by
Tanabe Pharma America, Inc. · Tanabe Pharma Corporation

Trials 4

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 13 trials
Phase 1 NCT05396235 Aug → Dec 2022 — Tanabe Pharma Corporation Completed No outcome recorded
Phase 1 NCT05240612 May 2022 → Sep 2023 tropical spastic paraparesis Tanabe Pharma Corporation Completed No outcome recorded
Phase 1 NCT04096950 Apr 2020 → Jan 2021 spinal cord injury Tanabe Pharma America, Inc. Completed No outcome recorded
Phase 21 trial
Phase 2 NCT04683848 Aug 2021 → Dec 2024 spinal cord injury Tanabe Pharma America, Inc. Completed No outcome recorded

Evidence & citations 7 cited values

Every value below carries the sentence it was read from. 5 sources stand behind the page.

FieldValueCited text
Known as UNASNEMAB ChEMBL registry synonym — accepted as the source's own label CHEMBL4650492 ↗
Known as MT-3921 ClinicalTrials.gov intervention name — accepted as the source's own label NCT04096950 ↗
3

NCT04683848 ↗

NCT05396235 ↗

NCT05240612 ↗

Known as rH116A3 ChEMBL registry synonym — accepted as the source's own label CHEMBL4650492 ↗
Action Inhibit “Repulsive guidance molecule A inhibitor” CHEMBL4650492 ↗
Modality Monoclonal antibody — CHEMBL4650492 ↗
Route Intravenous “MT-3921 Low dose, intravenous, single dosing” NCT04096950 ↗
Target RGMA “Repulsive guidance molecule A inhibitor” CHEMBL4650492 ↗