Drugs / ALN-4324
last change Jan 2026 re-read 3 minutes ago

ALN-4324

Developed for
type 2 diabetes mellitus
Investigated by
Alnylam Pharmaceuticals

Trials 2

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1/21 trial
Phase 1/2 NCT06845202 Mar 2025 → Aug 2027 expected type 2 diabetes mellitus Alnylam Pharmaceuticals Recruiting No outcome recorded
Phase 21 trial
Phase 2 NCT07465224 Jan 2026 → May 2027 expected type 2 diabetes mellitus Alnylam Pharmaceuticals Recruiting No outcome recorded

News releases announcing trial results or a regulatory action · 1

DateIssuerRelease
2025-02-25 Alnylam Pharmaceuticals Results Alnylam Highlights Significant Pipeline Progress and Platform Innovation at R&D Day alnylam.com ↗
At R&D Day, Alnylam will present preclinical data that demonstrate the potential for a highly desirable product profile, including approximately 90% knockdown of the target 22 days after a low-dose, subcutaneous injection, and improved insulin sensitivity without weight gain.

All press releases naming this drug 1 release

DateIssuerRelease

Evidence & citations 2 cited values

Every value below carries the sentence it was read from. 2 sources stand behind the page.

FieldValueCited text
Known as ALN-4324 ClinicalTrials.gov intervention name — accepted as the source's own label NCT06845202 ↗
1

NCT07465224 ↗

Route Subcutaneous “ALN-4324 will be administered subcutaneously (SC)” NCT06845202 ↗