Drugs / CAR-M-C-MET
last change May 2026 re-read 3 minutes ago

CAR-M-C-MET

Cell therapy

Developed for
malignant pancreatic neoplasm
Investigated by
Peking Union Medical College Hospital

Trials 1

20272028
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1 NCT07553793 May 2026 → Dec 2028 expected malignant pancreatic neoplasm Peking Union Medical College Hospital Not yet recruiting No outcome recorded

Evidence & citations 4 cited values

Every value below carries the sentence it was read from. 2 sources stand behind the page.

FieldValueCited text
Known as CAR-M-c-MET “Chimeric antigen receptor macrophages targeting c-MET(CAR-M-c-MET) inhibit pancreatic cancer progression and improve cytotoxic chemotherapeutic efficacy.” PMID 39643883 ↗ Dec 2024
1

NCT07553793 ↗

Action Deplete “CAR-M-c-MET cells demonstrated highly specific binding to pancreatic cancer cells and exhibited more phagocytosis and killing abilities than the pro-inflammatory polarized...” PMID 39643883 ↗ Dec 2024
Modality Cell therapy “CAR-M-C-MET) is a novel cellular therapy for these patients.” NCT07553793 ↗
Route Other “The final cell product is cryopreserved and later administered via intraperitoneal infusion.” NCT07553793 ↗