Drugs / anivamersen

Trials 4 · a red edge is where a trial was stopped

20082009201020112012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 11 trial
Phase 1 NCT01872572 Aug → Dec 2009 Regado Biosciences, Inc. Completed No outcome recorded
Phase 22 trials
Phase 2 NCT00932100 Jul 2009 → Jan 2011 acute coronary syndrome Regado Biosciences, Inc. Completed No outcome recorded
Phase 2 NCT00715455 Oct 2007 → Oct 2008 coronary artery disorder Regado Biosciences, Inc. Completed No outcome recorded
Phase 31 trial
Phase 3 NCT01848106 Sep 2013 → Aug 2014 coronary artery disorder Regado Biosciences, Inc. Terminated No outcome recorded

Evidence & citations 4 cited values

Every value below carries the sentence it was read from. 5 sources stand behind the page.

FieldValueCited text
Known as anivamersen “The REG2 anticoagulation system consists of pegnivacogin, a subcutaneously administered aptamer factor IXa inhibitor, and its intravenous control agent, anivamersen.” PMID 22500821 Jul 2012
2

“the REG1 system consisting of pegnivacogin, an aptameric factor IXa inhibitor, and its controlling agent anivamersenPMID 24929350 Aug 2014

NCT01848106

Known as RB007 “REG1, an anticoagulation system, consists of RB006 (pegnivacogin), an RNA oligonucleotide factor IXa inhibitor, and RB007 (anivamersen), its complementary controlling agent.” PMID 21315207 Feb 2011
1

“The antidote component, RB007, is a complementary nucleic acid that binds to and neutralizes RB006.” NCT00715455

Modality Oligonucleotide (other) “The antidote component, RB007, is a complementary nucleic acid that binds to and neutralizes RB006.” NCT00715455
Route Intravenous “The antidote (RB007) is administered as an IV bolus dose” NCT00715455