Drugs / INT131
last change Dec 2016 re-read 2 minutes ago

INT131

also known as AMG-131 · CHS-131 · Ibrigampar · INT131 besylate · T0903131 · T131

Other / unclassified targets PPARG

Developed for
type 2 diabetes mellitus · relapsing-remitting multiple sclerosis
Investigated by
InteKrin Therapeutics, Inc.

Trials 3 · a red edge is where a trial was stopped

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PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 2 NCT02638038 Feb 2015 → Dec 2016 relapsing-remitting multiple sclerosis InteKrin Therapeutics, Inc. Completed No outcome recorded
Phase 2 NCT00631007 Feb 2008 → Aug 2009 type 2 diabetes mellitus InteKrin Therapeutics, Inc. Completed No outcome recorded
Phase 2 NCT00952445 Dec 2003 → Jun 2004 type 2 diabetes mellitus InteKrin Therapeutics, Inc. Completed No outcome recorded

Evidence & citations 10 cited values

Every value below carries the sentence it was read from. 5 sources stand behind the page.

FieldValueCited text
Known as INT131 ClinicalTrials.gov intervention name — accepted as the source's own label NCT02638038
1

NCT00631007

Known as AMG-131 ChEMBL registry synonym — accepted as the source's own label CHEMBL1236924
Known as CHS-131 ChEMBL registry synonym — accepted as the source's own label CHEMBL1236924
Known as Ibrigampar ChEMBL registry synonym — accepted as the source's own label CHEMBL1236924
Known as INT131 besylate “OBJECTIVE: INT131 besylate is a potent, nonthiazolidinedione, selective peroxisome proliferator-activated receptor γ (PPARγ) modulator (SPPARM) designed to improve glucose...” PMID 24722496 Apr 2014
Known as T0903131 ClinicalTrials.gov intervention name — accepted as the source's own label NCT00952445
Known as T131 ChEMBL registry synonym — accepted as the source's own label CHEMBL1236924
Modality Other / unclassified “INT131 besylate is a potent, nonthiazolidinedione, selective peroxisome proliferator-activated receptor γ (PPARγ) modulator (SPPARM)” PMID 24722496 Apr 2014
Route Oral “Once-daily, oralNCT00631007
Target PPARG “selective peroxisome proliferator-activated receptor γ (PPARγ) modulator” PMID 24722496 Apr 2014