TSND-201 (Methylone): A Rapid-Acting Neuroplastogen that Stimulates Neurite Outgrowth

Summary of poster presentation: TSND-201 increases neurite outgrowth and branching via well-studied mechanisms (i.e., monoamines, neurotrophins, and mTor). Preclinical results add to understanding of TSND-201’s mechanism of action. Demonstrates direct neurotrophic effects of TSND-201 for the first time. Confirms that neuroplastic effects are mediated by TSND-201’s known pharmacological targets (serotonin, norepinephrine, dopamine transporters) – connecting the dots between primary pharmacology and long-lasting neuroplasticity. Underscores TSND-201’s potential as a rapid, robust, and long-lasting pharmacotherapy for PTSD and other CNS disorders. View Poster

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