New Online Commentary in UroToday on Fexapotide BPH Clinical Trial Results Publication in World Journal of Urology
2018-04-10 · Nymox Corporation · original nymox.com ↗
For Further Information Contact: Erik Danielsen Nymox Pharmaceutical Corporation 1-800-93NYMOX www.nymox.com For Immediate Release: New Online Commentary in UroToday on Fexapotide BPH Clinical Trial Results Publication in World Journal of Urology HASBROUCK HEIGHTS, NJ (April 10, 2018) A new on line published commentary about Nymox’s (NASDAQ: NYMX) Fexapotide 2018 clinical trial results publication in World Journal of Urology has newly appeared today on UroToday in its "Beyond the Abstract" section, along with t he abstract of the World Journal of Urology article. The additional commentary was authored by Dr. Neal Shore, lead author of the peer review World Journal article, and Dr. Ronald Tutrone, the first co-author of the article. The Beyond the Abstra ct commentary is entitled “Fexapotide Triflutate: Results of Long-Term Safety and Efficacy Trials of A Novel Injectable Therapy For Symptomatic Prostate Enlargement - Beyond the Abstract”. The World Journal of Urology article is entitled "Fexapotide Triflutate: Results of Long-Term Safety and Efficacy Trials of A Novel In jectable Therapy For Symptomatic Prostate Enlargement" (https://doi.org/10.1007/s00345-018-2185-y). According to the new "Beyond the Abstract" commentary, "F exapotide triflutate (FT) is a first in class protein injectable designed for safe and relatively painless office treatment of BPH. It works by selective promotion of apoptosis in prostate glandular cells. FT is administered under transrectal ultrasound visualization using a standard 22 gauge needle. Over 1700 patients and controls have been inject ed with FT since the first U.S. clinical trials in 2002, and there have been no molecular related adverse event s described. There is no need for a urinary catheter or anesthesia. Clinically significant improvements from baseline symptoms may occur within 1-2 weeks.” The commentary concludes, “Regarding a molecular therapy for BPH, there continues to exist an unmet need for patient treatment whereby symptoms can be effectively treated while avoiding associated sexual dysfunction, catheterization and significant anesthetic requirements. FT is in late stage development and has potential to be a fundamentally new addition to office based treatment for BPH patients.” The new commentary also features a review and illustration Figures. The World Journal of Urology articl e was also co-authored by Mitchell Ef ros, MD, FACS (Accumed Research, Garden City, NY); Mohamed Bidair, MD (San Diego Clinical Trials, San Diego, CA); Barton Wachs, MD (Atlantic Urology Medical Group, Long Beach, CA); Susan Kalota, MD (Urological Associates of Southern Arizona, Tucson, AZ); Sheldon Freedman, MD, FACS (Freedman Urology, Las Vegas, NV); James Bailen, MD, FACS (First Urology, Louisville, KY); Richard Levin, MD, FACS (Chesapeake Urology Research Associates, Towson, MD); Stephen Richardson, MD (Jean Brown Research, Salt Lake City, UT); Jed Kaminetsky, MD, FACS (University Urology, New York, NY); Jeffrey Snyder, MD, FACS (Genitourinary Surgical Consultants, Denver, CO); Barry Shepard, MD, FACS (Urological Surgeons of Long Island, Garden City, NY); Kenneth Goldberg, MD, FACS (U T Southwestern Dept of Urology, Lewisville, TX); Alan Hay, MD, FACS (Willamette Urology, Salem, OR); Steven Gange, MD, FACS (Summit Urology Group, Salt Lake City, UT); Ivan Grunberger, MD, FACS (Brooklyn Urology, Brooklyn, NY). Nymox's lead drug Fexapotide has been in development for over 10 years and has been te sted by expert clinical trial investigative teams in over 70 distinguished clinical trial centers throughout the US, and has been found after 7 years of prospective placebo controlled double blind st udies of treatment of 995 U.S. men with prostate enlargement to not only show clinically meaningful and du rable relief of BPH symptoms, but also to show a major reduction in the incidence of prostate cancer, compared to placebo and compared to the known and expected normal incidence of the disease. The same clinical progr am has also shown in a long-term blinded placebo group study an 82-95% reduction in the number of these patients who required surgery after they received Fexapotide in NEWS RELEASE the trial, as compared to patients who did not receive Fexapotide but instead later received conventional approved BPH treatments (p<.0001). For more information please contact [email protected] or 800-936-9669. Forward Looking Statements To the extent that statements contained in this press rel ease are not descriptions of historical facts regarding Nymox, they ar e forward-looking statements reflecting t he current beliefs and expectations of mana gement made pursuant to the safe harbor provisions of the Private Secu rities Litigation Reform Act of 1995, including st atements regarding the need for new options to treat BPH and prostate cancer, the potential of Fexapotide to tr eat BPH and prostate cancer and the estimated timing of further developments for Fexapotide. Such forward-looking statements invo lve substantial risks and uncert ainties that could cause our clinical development program, future results, performance or achievements to differ significantly from those expressed or implied by the forward-looking statements. Such risks and uncertainties include, among others, the uncertainties inherent in the clinic al drug development process, including the r egulatory approval process, the timing of Nymox's regulatory filings, Nymox's substantial dependence on Fexapot ide, Nymox's commercialization plans and effort s and other matters that could affect the availability or commercial potential of Fexapotide. Nymox undertakes no obligation to update or revise any forward looking statements. For a further description of the risks and uncertainties that could cause ac tual results to differ from those expressed in these forward-looking statem ents, as well as risks relating to the business of Nymox in general, see Nymox's current and future reports filed with the U.S. Securities and Exchange Commission, including its Annual Report on Form 20-F for the year ended December 31, 2017, and its Quarterly Reports.
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