Sydnexis Wins Poster Session at Vision by Design 2025: Effect of pH and BAK on Pupil Dilation Following Low-dose Atropine Administration in Dutch Belted Rabbits

We’re proud to share that Sydnexis was named the poster session winner at Vision by Design 2025, the annual conference hosted by the American Academy of Orthokeratology and Myopia Control (AAOMC). This event brings together clinicians, researchers, and industry leaders dedicated to advancing the science and practice of myopia management. Nick Ruth, Chief Commercial Officer at Sydnexis, presents the award-winning poster during Vision by Design 2025. Our poster presents findings from a preclinical study evaluating how formulation factors—specifically pH and the preservative benzalkonium chloride (BAK)—affect the pharmacologic response to low-dose atropine. Results showed that a neutral pH formulation containing BAK produced greater and more sustained pupil dilation compared to an acidified, BAK-free formulation, suggesting that these variables can significantly influence drug bioavailability and efficacy in low-dose atropine therapies You can view the full poster, “Effect of pH and BAK on Pupil Dilation Following Low-dose Atropine Administration in Dutch Belted Rabbits,” below. VIEW AND DOWNLOAD POSTER HERE AAOMC-Poster_Pupillometry-Rabbit-Study_Final We respect your privacy By clicking “Accept” or continuing to use this website, you consent to the use of cookies, tags, pixels, and similar technologies set by us and our third-party partners. We use these tools to personalize your experience, for marketing, and for analytics. You may block some of these by clicking “Reject” or by visiting the preference center (click “Customize”). By using this site you agree to our Privacy Policy and Terms and Conditions . Functional Functional Always active The technical storage or access is strictly necessary for the legitimate purpose of enabling the use of a specific service explicitly requested by the subscriber or user, or for the sole purpose of carrying out the transmission of a communication over an electronic communications network. Preferences Preferences The technical storage or access is necessary for the legitimate purpose of storing preferences that are not requested by the subscriber or user. Statistics Statistics The technical storage or access that is used exclusively for statistical purposes. The technical storage or access that is used exclusively for anonymous statistical purposes. Without a subpoena, voluntary compliance on the part of your Internet Service Provider, or additional records from a third party, information stored or retrieved for this purpose alone cannot usually be used to identify you. Marketing Marketing The technical storage or access is required to create user profiles to send advertising, or to track the user on a website or across several websites for similar marketing purposes. Manage options Manage services Manage {vendor_count} vendors Read more about these purposes Accept Reject Customize Save preferences Customize {title} {title} {title}

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