VOLUNTARY ANNOUNCEMENT - NEW TARGET ANTI-TUMOR DRUG "SYHA1807" WAS GRANTED CLINICAL TRIAL APPROVAL

Hong Kong Exchanges and Clearing Limited and The Stock Exchange of Hong Kong Limited take no responsibility for the contents of this announcement, make no representation as to its accuracy or completeness and expressly disclaim any liability whatsoever for any loss howsoever arising from or in reliance upon the whole or any part of the contents of this announcement. CSPC PharmaCeutiCal GrouP limited ʮ ̡ (Incorporated in Hong Kong with limited liability) (Stock Code: 1093) VoluNtarY aNNouNCeme Nt NeW tarG et aNti- tumor druG “SYha1807” WaS G raNted CliNiCal trial aPProVal The board of directors (the “ Board”) of CSPC Pharmaceutical Group Limited (the “ Company ”, together with its subsidiaries, the “Group”) is pleased to announce that “SYHA1807” (the “Product”) developed by the Group was granted approval by the National Medical Products Administration of the People’s Republic of China to conduct clinical trials in China. The Product has a number of patent applications in China and overseas. The Product is a new type of small-molecule kinase inhibitor and currently there is no product of the same type available in the global market. The clinical indication approved is for the treatment of small-cell lung cancer. The pre-clinical studies indicated that the Product has an outstanding efficacy in respect of in vitro and in vivo anti-tumor activity and good safety, providing a promising prospect of demonstrating good efficacy for the treatment of small-cell lung cancer in the clinical trials. The Group will endeavor to push forward the clinical trials of the Product and strive to launch the Product as soon as possible. By Order of the Board CSPC Pharmaceutical Group limited Cai dongchen Chairman Hong Kong, 29 July 2019 As at the date of this announcement, the Board comprises Mr. CAI Dongchen, Mr. ZHANG Cuilong, Mr. WANG Zhenguo, Mr. PAN Weidong, Mr. WANG Huaiyu, Dr. LU Hua, Dr. LI Chunlei, Dr. WANG Qingxi and Mr. CHAK Kin Man as executive directors; Mr. LEE Ka Sze, Carmelo as non-executive director; and Mr. CHAN Siu Keung, Leonard, Mr. WANG Bo, Professor LO Yuk Lam, Dr. YU Jinming and Mr. CHEN Chuan as independent non-executive directors.

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