Antengene Presents Compelling Preclinical Data on Two Programs at the Society for Immunotherapy of Cancer (SITC) Annual Meeting on November 12, 2021

- ATG-101, a novel PD-L1/4-1BB bispecific antibody, shows potent in vivo anti-tumor efficacy in checkpoint inhibitor resistant/relapsed models while mitigating liver toxicity risk, computational analysis adds support to dosing strategy - ATG-017, an ERK1/2 inhibitor, in vivo combination supports clinical development strategy Shanghai and Hong Kong, PRC, November 15, 2021 – Antengene Corporation Limited (“Antengene”, SEHK: 6996.HK), a leading innovative global biopharmaceutical company dedicated to discovering, developing and commercializing first-in-class and/or best-in-class therapeutics in hematology and oncology, today announced the presentation of three posters at the Society for Immunotherapy of Cancer (SITC) Annual Meeting in Washington D.C. (https://www.sitcancer.org/home). “Antengene is very pleased to present preclinical data on two of our Phase I programs, for ATG-101 and ATG-017, at the 2021 SITC meeting on November 12, 2021. The unique mechanisms, promising preclinical safety and activity of these exciting new compounds are very much in keeping with Antengene’s mission to develop first-in-class, best-in-class medicines for cancer,” said Jay Mei, M.D., Ph.D., Founder, Chairman and Chief Executive Officer of Antengene. Dr. Mei continued, “These presentations also highlight the breadth and depth of Antengene’s drug development capabilities. The Antengene management team and I look forward to reviewing these posters, detailed below, and the Company’s exciting portfolio at our upcoming R&D Day, planned for November 16th (virtual, details below) and November 18th (in person, details below).” Summary of Poster Presentations Poster #893: ATG-101: Active in “Cold” tumors, No Preclinical Liver Toxicity ATG-101 is a PD-L1 / 4-1BB bi-specific antibody that was designed to activate tumor infiltrating lymphocytes and inhibit immune checkpoints, without inducing liver toxicity. Antengene presented data from in vitro and in vivo studies that evaluated ATG-101 activity in several T-cell activation assays and multiple in vivo models, including those resistant to anti-PD(L)1 therapies. Data in the poster showed that ATG-101 was active in anti-PD-L1 resistant and relapsed tumor models. In addition, ATG-101 increased the activation of T-cells and exhausted T-cells upon PD-L1 crosslinking (required for ATG-101 activity), rendering “cold” tumors “hot”. Importantly, ATG-101 showed no liver toxicity in a GLP toxicity study (differentiating the drug vs other 4-1BB targeted monoclonals/bi-specifics) and did not induce cytokine release syndrome in an in vitro assay. ATG-101’s unique safety and efficacy properties make it a promising potential therapy for solid tumors and non-Hodgkins lymphoma. Poster #608: Promising ATG-017 in vivo Combination Study Add to Clinical Strategy ATG-017 is a potent small molecule kinase inhibitor targeting the extracellular signal-related kinases 1 and 2 (ERK1/2). Antengene presented data on an in vivo study that evaluated ATG-017 in combination with an anti-PD-L1 monoclonal antibody (atezolizumab), in an aggressive, immune checkpoint inhibitor resistant mouse cancer model. Data in the poster showed that the combination enhanced the antitumor efficacy as well as increasing the percentage of infiltrating CD8+ T cells, NK cells, CD8:CD4 ratio and M1:M2 macrophage ratio in the tumor microenvironment, rendering a “cold” tumor “hot”. These results demonstrated that ATG-017 has potential synergy with immune checkpoint inhibitors, providing a rationale for exploring combination therapy in the clinic in the pursuit of improved efficacy in solid tumors, including those resistant to checkpoint inhibitions. Poster# 227: Computational Analysis Tool Enables ATG-101 Clinical Dose Selection Bispecific antibody ATG-101 acts by forming a trimer (comprised of ATG-101 bound to PD-L1 and 4-1BB expressing cells) that activates tumor infiltrating lymphocytes and inhibits immune checkpoints. Measuring trimeric complexes is important in defining optimal clinical doses but is very challenging to do in the clinic. Antengene and its collaborators at Applied BioMath, LLC reported on the development of a computational semi-mechanistic pharmacology model that could be used to define the clinical dose of ATG-101. It works by simulating in vivo tumor growth inhibition and predicting trimer formation, free drug levels and receptor occupancy over time. This work has enabled Antengene to define a clinically effective dose range of ATG-101 that induces >90% PD-L1 receptor occupancy, a key metric of drug activity. This valuable pharmacology tool, which may also be applied across other compounds in Antengene’s pipeline, reflects the Company’s enthusiasm to utilize novel technologies and partnerships to enhance drug development capabilities. Details on the posters, published on the SITC website, are shown below: Abstract Number: 227 Title: A computational semi-mechanistic pharmacology model of ATG-101, a PD-L1/4-1BB bispecific antibody for treatment of solid tumors and NHL Time: 7:00-17:00 EST, November 12-14, 2021 Presenter： Dr. David C. Flowers, Applied BioMath, LLC First Author: Dr. David C. Flowers, Applied BioMath, LLC Abstract Number: 608 Title: Synergistic effect of the combination of ATG-017, an ERK1/2 inhibitor, and immune checkpoint inhibitor in preclinical cancer models Time: 7:00-17:00 EST, November 12-14, 2021 Presenter： Dr. Bing Hou, Antengene Corporation Limited First Author: Dr. Peng Chen, Antengene Corporation Limited Abstract Number: 893 Title: ATG-101, a novel PD-L1/4-1BB bispecific antibody, augments anti-tumor immunity through immune checkpoint inhibition and PDL1-directed 4-1BB activation Time: 7:00-17:00 EST, November 12-14, 2021 Presenter： Dr. Bing Hou, Antengene Corporation Limited First Author: Dr. Hui Yuwen, Antengene Corporation Limited About ATG-101 ATG-101 is a novel PD-L1/4-1BB bi-specific antibody being developed for the treatment of multiple kinds of cancer. ATG-101 can activate anti-tumor immune effectors by simultaneously blocking the binding of PD-L1/PD-1 and inducing 4-1BB stimulation. In PD-L1 over-expressed cancer cells, ATG-101 has shown potent PD-L1 crosslinking-dependent 4-1BB agonist activity, thus potentially enhancing therapeutic efficacy, whilst mitigating risk of hepatoxicity. Antengene has received U.S. FDA approval for the IND for a Phase I trial of ATG-101 in solid tumors and non-Hodgkins lymphoma and is currently conducting a Phase I study of ATG-101 in Australia for the treatment of patients with metastatic/advanced solid tumors and non-Hodgkin lymphoma. About ATG-017 ATG-017 is a potent and selective small molecule extracellular signal-regulated kinases 1 and 2 (ERK1/2) inhibitor. ERK1/2 are related protein-serine/threonine kinases that function as terminal kinases in the RAS-MAPK signal transduction cascade. This cascade regulates a large variety of cellular processes, including proliferation. The RAS-MAPK pathway is dysregulated in more than 30% of human cancers with the most frequent alterations being observed in RAS or BRAF genes across multiple tumor types. An ERK inhibitor enables the targeting of both RAS and BRAF mutant diseases. In nonclinical pharmacology studies, ATG-017 has demonstrated potent inhibition of ERK1/2 enzyme activity and tumor growth in vitro and in vivo. Antengene is conducting an open-label Phase I, dose-escalation study of ATG-017 in Australia for the treatment of patients with advanced solid tumors and hematologic malignancies. About Antengene’s R&D Day Antengene’s R&D Day will include presentations from Dr. Jay Mei, Founder, Chairman and CEO; Mr. John Chin, Chief Business Officer; Dr. Kevin Lynch, Chief Medical Officer; Dr. Bo Shan, Chief Scientific Officer, and other Company management. The meetings will be held virtually in English on November 16, 2021, and on-site in Mandarin on November 18, 2021. A live webcast will be available on the Antengene website under “Investor Relations”, on the Event Calendar page. To attend the event, please register in advance at links below: R&D Day English Session – Virtual Conference • Date: Tuesday, November 16, 2021 • Time: 8:30 am – 11: 30 am, Eastern Time / 9:30 pm – 12: 30 am, Beijing Time • Register at: https://www.micecube.com/sign/pfrKl2 R&D Day Mandarin Session – Live Webcast of On-Site Meeting • Date: Thursday, November 18, 2021 • Time: 1:30 pm – 5:30 pm, Beijing Time • Register at: https://www.micecube.com/sign/hylbfK About Antengene Antengene Corporation Limited (“Antengene”, SEHK: 6996.HK) is a leading clinical-stage R&D- driven global biopharmaceutical company focused on innovative first-in-class/best-in-class therapeutic medicines for oncology and other life-threatening diseases. Driven by its vision of “Treating Patients Beyond Borders”, Antengene aims to provide the most advanced anti-cancer drugs to patients in the Asia Pacific Region and around the world. Since initiating operations in 2017, Antengene has obtained 18 investigational new drug (IND) approvals, submitted 6 new drug applications (NDAs) in multiple Asia Pacific markets, with the NDA for selinexor/ATG-101 in South Korea already approved through a priority review process. Leveraging partnerships as well as in-house drug discovery, Antengene has built a broad and expanding pipeline of 13 clinical and pre-clinical assets. The Company has global rights on 8 programs and Asia Pacific rights, including the Greater China region, on 5 programs. Forward-Looking Statements The forward-looking statements made in this article relate only to the events or information as of the date on which the statements are made in this article. Except as required by law, we undertake no obligation to update or revise publicly any forward-looking statements, whether as a result of new information, future events or otherwise, after the date on which the statements are made or to reflect the occurrence of unanticipated events. You should read this article completely and with the understanding that our actual future results or performance may be materially different from what we expect. In this article, statements of, or references to, our intentions or those of any of our Directors or our Company are made as of the date of this article. Any of these intentions may alter in light of future development. For a further discussion of these and other factors that could cause future results to differ materially from any forward-looking statement, see the section titled “Risk Factors” in our periodic reports filed with the Hong Kong Stock Exchange and the other risks and uncertainties described in the Company’s Annual Report for year ended December 31, 2020, and subsequent filings with the Hong Kong Stock Exchange. Privacy Notice Last updated: July 15, 2022 This Privacy Notice describes Our policies and procedures on the collection, use and disclosure of Your information when You use the Service, and tells You about Your privacy rights and how the law protects You. We use Your Personal data to provide and improve the Service. By using the Service, You agree to the collection and use of information in accordance with this Privacy Notice. If You do not agree to these terms, You are not authorized to use Our Service. 1. Definitions The following definitions shall have the same meaning regardless of whether they appear in singular or in plural. For the purposes of this Privacy Notice: Affiliate means with respect to a specified person or entity, any other person or entity that directly, or indirectly through one or more intermediaries, controls or is controlled by, or is under common control with, the specified person or entity, and the term “control” (including the terms controlling, controlled by and under common control with) means the possession, direct or indirect, of (i) the power to direct or cause the direction of the management and policies of an entity, whether through the ownership of voting securities, by contract or otherwise or (ii) 50% or more of the issued share capital of an entity. Antengene (referred to as either "Antengene", "We", "Us" or "Our" in this Agreement) refers to Antengene Corporation Limited and its Affiliates. Cookies are small files that are placed on Your computer, mobile device or any other device by a website, containing the details of Your browsing history on that website among its many uses. Device means any device that can access the Service such as a computer, a cellphone or a digital tablet. Personal Information is any information that relates to an identified individual or can be used to identify a person, either directly or indirectly (e.g. by combining different sets of indirect indentifiers). Service refers to the Website and its mobile applications. Service Provider means any third party that processes Personal Information under the instructions of Antengene or to which Antengene discloses information for use on Antengene’s behalf. Usage Data refers to data collected automatically, either generated by the use of the Service or from the Service infrastructure itself (for example, the duration of a page visit). Website refers to Antengene Website, accessible from antengene.com You means the individual accessing or using the Service, or the legal entity on behalf of which such individual is accessing or using the Service, as applicable. 2. Information We Collect 2.1 Personal Information While using Our Service, We may ask You to provide Us with certain personally identifiable information that can be used to contact or identify You. Personally identifiable information may include, but is not limited to Your name, postal address, telephone number, email address, date of birth, identification numbers, and health, financial and professional information. 2.2 Usage Data Usage Data is collected automatically when using the Service. a) Usage Data may include information such as Your Device's Internet Protocol address (e.g. IP address), browser type, browser version, the pages of our Service that You visit, the time and date of Your visit, the time spent on those pages, unique device identifiers and other diagnostic data. b) When You access the Service by or through a mobile device, We may collect certain information automatically, including, but not limited to, the type of mobile device You use, Your mobile device unique ID, the IP address of Your mobile device, Your mobile operating system, the type of mobile Internet browser You use, unique device identifiers and other diagnostic data. c) We may also collect information that Your browser sends whenever You visit our Service or when You access the Service by or through a mobile device. 2.3 Tracking Technologies and Cookies We use Cookies and similar tracking technologies to track the activity on Our Service and store certain information. Tracking technologies used are beacons, tags, and scripts to collect and track information and to improve and analyze Our Service. The technologies We use may include: a) Cookies or Browser Cookies. A cookie is a small file placed on Your Device. You can instruct Your browser to refuse all Cookies or to indicate when a Cookie is being sent. However, if You do not accept Cookies, You may not be able to use some parts of our Service. Unless you have adjusted Your browser setting so that it will refuse Cookies, our Service may use Cookies. b) Flash Cookies. Certain features of our Service may use local stored objects (or Flash Cookies) to collect and store information about Your preferences or Your activity on our Service. Flash Cookies are not managed by the same browser settings as those used for Browser Cookies. c) Web Beacons. Certain sections of our Service and our emails may contain small electronic files known as web beacons (also referred to as clear gifs, pixel tags, and single-pixel gifs) that permit Antengene, for example, to count users who have visited those pages or opened an email and for other related website statistics (for example, recording the popularity of a certain section and verifying system and server integrity). 3. Use of Your Personal Information 3.1 Antengene may use Personal Information for the following purposes: a) To provide and maintain our Service , including to monitor the usage of our Service, site administration and maintenance, and security improvements. b) To provide You with general health information (such as information on certain health conditions) as well as information about Our products and services;. c) To respond to Your requests: To attend and manage Your requests, inquiries, or applications to Us. d) For business transfers: We may use Your information to evaluate or conduct a merger, divestiture, restructuring, reorganization, dissolution, or other sale or transfer of some or all of Our assets, whether as a going concern or as part of bankruptcy, liquidation, or similar proceeding, in which Personal Information held by Us about our Service users is among the assets transferred. e) For other purposes : We may use Your information for other purposes where it is necessary for Our legitimate interest as a company, including but not limited to research and development, regulatory reporting, contract management, fulfillment, analytics, fraud prevention, corporate governance, reporting, legal compliance, data analysis, identifying usage trends, determining the effectiveness of our promotional campaigns and to evaluate and improve our Service, products, services, marketing and your experience. 3.2 We will not sell, share, or otherwise distribute Your Personal Information to third parties except as provided in this Privacy Notice. We may share Your Personal Information in the following situations: a) With Service Providers: We may share Your Personal Information with Service Providers for further processing, such as to monitor and analyze the use of our Service, or to contact You. These Service Providers have contracted with Us to only use the Personal Information for the purpose(s) for which the data were originally collected or may otherwise be lawfully processed, not to sell Your Personal Information to other third parties, and not to disclose it to other third parties except as may be required by law, as permitted by Us or as stated in this Privacy Policy. b) For business transfers: We may share or transfer Your Personal Information in connection with, or during negotiations of, any merger, sale of Antengene assets, financing, or acquisition of all or a portion of Our business to another company. c) With Affiliates: We may share Your information with Our Affiliates, in which case we will require those Affiliates to honor this Privacy Notice. d) With Your consent : We may disclose Your Personal Information for any other purpose with Your consent. 3.3 Retention of Your Personal Information a) Antengene will retain Your Personal Information only for as long as is necessary for the purposes set out in this Privacy Notice. We will retain and use Your Personal Information to the extent necessary to comply with our legal obligations (for example, if we are required to retain your data to comply with applicable laws), resolve disputes, and enforce our legal agreements and policies. b) Antengene will also retain Usage Data for internal analysis purposes. Usage Data is generally retained for a shorter period of time, except when this data is used to strengthen the security or to improve the functionality of Our Service, or We are legally obligated to retain this data for longer time periods. 4. Sharing Your Personal Information 4.1 Your information, including Personal Information, is processed at Antengene's operating offices and in any other places where the parties involved in the processing are located. It means that this information may be transferred to — and maintained on — computers located outside of Your state, province, country or other governmental jurisdiction where the data protection laws may differ than those from Your jurisdiction. Therefore, by using the Service or otherwise providing information to Us, You hereby expressly consent to the transfer of Your Personal Information outside Your country or region. 4.2 If Antengene is involved in a merger, acquisition or asset sale, Your Personal Information may be transferred. We will provide notice before Your Personal Information is transferred and becomes subject to a different Privacy Notice. 4.3 Under certain circumstances, Antengene may be required to disclose Your Personal Information if required to do so by law or in response to valid requests by public authorities (e.g. a court or a government agency). 4.4 Antengene may disclose Your Personal Information in the good faith belief that such action is necessary to: a) Comply with a legal obligation ; b) Protect and defend the rights or property of Antengene ; c) Prevent or investigate possible wrongdoing in connection with the Service ; d) Protect the personal safety of Users of the Service or the public ; e) Protect against legal liability 5. Data Security The security of Your Personal Information is important to Us, and We use commercially reasonable administrative, technical, personnel-related, and physical security measures designed to safeguard the Personal Information in Our possession against loss, theft and unauthorized use, disclosure, or modification. But remember that no method of transmission over the Internet, or method of electronic storage is 100% secure. We cannot guarantee its absolute security. In the event of a security incident involving Your Personal Information, as required by applicable laws, We will inform You in a timely manner and report the incident to relevant regulatory authorities. 6. Children's Privacy We are committed to protecting the privacy of children. The Service is not intended for, or designed to attract, children under the age of 18. We do not knowingly collect personally identifiable information from anyone under the age of 18. If You are a parent or guardian and You are aware that Your child has provided Us with Personal Information, please contact Us. If We become aware that We have collected Personal Information from anyone under the age of 18 without verification of parental consent, We take steps to remove that information from Our servers. 7. Links to Other Websites 7.1 Our Service may contain links to other websites that are not operated by Us. If You click on a third-party link, You will be directed to that third party's site. We strongly advise You to review the Privacy Notice of every site You visit. 7.2 We have no control over and assume no responsibility for the content, privacy policies or practices of any third-party sites or services. 8. Changes to this Privacy Notice 8.1 We may update Our Privacy Notice from time to time. We will notify You of any changes by posting the new Privacy Notice on this page. 8.2 We will let You know via email and/or a prominent notice on Our Service, prior to the change becoming effective and update the "Last updated" date at the top of this Privacy Notice. 8.3 You are advised to review this Privacy Notice periodically for any changes. Changes to this Privacy Notice are effective when they are posted on this page. 9. Contact Us You may contact us at any time if You have questions about this Privacy Notice. Under applicable data protection laws, You may have the right to object to or request restriction of processing of Your Personal Information and to request access to, rectification, erasure and portability of the Personal Information We hold about You, subject to certain exceptions prescribed by law. To reach Us, please send an email to: [email protected] , and we shall endeavor to answer Your inquiry as soon as reasonably possible in compliance with applicable laws. Terms and Conditions Last updated: July 15, 2022 Please read these Terms and Conditions carefully before using Our Service. 1. Definitions The following definitions shall have the same meaning regardless of whether they appear in singular or in plural. For the purposes of these Terms and Conditions: Affiliate means with respect to a specified person or entity, any other person or entity that directly, or indirectly through one or more intermediaries, controls or is controlled by, or is under common control with, the specified person or entity, and the term “control” (including the terms controlling, controlled by and under common control with) means the possession, direct or indirect, of (i) the power to direct or cause the direction of the management and policies of an entity, whether through the ownership of voting securities, by contract or otherwise or (ii) 50% or more of the issued share capital of an entity. Antengene (referred to as either "Antengene", "We", "Us" or "Our" in this Agreement) refers to Antengene Corporation Limited and its Affiliates. Device means any device that can access the Service such as a computer, a cellphone or a digital tablet. Service refers to the Website and its mobile applications. Terms and Conditions (also referred as "Terms") mean these Terms and Conditions that form the entire agreement between You and Antengene regarding the use of the Service. Third-party Social Media Service means any services or content (including data, information, products or services) provided by a third-party that may be displayed, included or made available by the Service. Website refers to Antengene Website, accessible from https://www.antengene.com/ You means the individual accessing or using the Service, or Antengene, or other legal entity on behalf of which such individual is accessing or using the Service, as applicable. 2. Acknowledgment 2.1 These are the Terms and Conditions governing the use of this Service and the agreement that operates between You and Antengene. These Terms and Conditions set out the rights and obligations of all users regarding the use of the Service. 2.2 Your access to and use of the Service is conditioned on Your acceptance of and compliance with these Terms and Conditions. These Terms and Conditions apply to all visitors, users and others who access or use the Service. If You disagree with any part of these Terms and Conditions then You may not access the Service. 2.3 By accessing or using the Service You represent and warrant that (1) You have the legal capacity and You agree to be bound by these Terms and Conditions; (2) You are not a minor in the jurisdiction in which You reside; (3) You will not access or use the Service through automated or non-human means, whether through a bot, script, or otherwise; (4) You will not access or use the Service for any illegal or unauthorized purposes; and (5) Your use of the Service will not violate any applicable law or regulation. 2.4 Your access to and use of the Service is also conditioned on Your acceptance of and compliance with the Privacy Policy of Antengene. Our Privacy Policy describes Our policies and procedures on the collection, use and disclosure of Your personal information when You use the Service and tells You about Your privacy rights and how the law protects You. Please read Our Privacy Policy carefully before using Our Service. 3. Forward Looking Statement 3.1 The Service may contain forward-looking statements regarding Antengene’s future operating or financial performance, business plans and prospects, and Our expectations regarding clinical trials, development timelines, and discussions with regulatory authorities related to drugs and drug candidates under development by Us and Our collaboration partners. 3.2 These forward-looking statements relate only to the events or information as of the date on which the statements are made. You should read these statements completely and with the understanding that Our actual future results or performance may be materially different from what We expect. In these statements of, or references to, Our intentions or those of any of Our directors or Our Company are made as of the date of those statements. Any of these intentions may alter in light of future development. For a further discussion of these and other factors that could cause future results to differ materially from any forward-looking statement, see the section titled “Risk Factors” in Our periodic reports filed with the Hong Kong Stock Exchange and the other risks and uncertainties described in Antengene’s Annual Report, and subsequent filings with the Hong Kong Stock Exchange. 3.3 Except as required by law, We undertake no obligation to update or revise publicly any forward-looking statements, whether as a result of new information, future events or otherwise, after the date on which the statements are made or to reflect the occurrence of unanticipated events. 4. Content and License 4.1 Antengene and its Affiliates, licensors, partners, providers, and their respective successors and assigns retain sole and exclusive ownership of all worldwide right, title and interest, including all copyrights, patent rights, trade secret rights, trademark rights, and other intellectual property and proprietary rights, in and to the Service, including all text, graphics and images, data, information, reports, software, tools, links and resources comprised in the Service or provided through the Service, as well as all technologies used by Antengene to provide and operate the Service. Other than a limited license to use as provided below, You have and acquire no other right or license with respect to the Service or any portion or component thereof. Unless expressly authorized by applicable law or in writing by Antengene, You may not copy, reproduce, publicly perform or display, transmit, modify or otherwise create derivative works from, sell, distribute, or otherwise make unauthorized use of the Service or any portion or component thereof. Any unauthorized use of the Service or any portion or component thereof is strictly prohibited and may result in civil and/or criminal penalties. There are no implied rights or licenses granted to You under these Terms. 4.2 Subject to Your compliance with these Terms and Conditions and all applicable laws and regulations, Antengene grants You a revocable, non-exclusive, non-transferable, non-sublicensable, limited personal license to access the Service for Your lawful personal and noncommercial uses. As a condition of Your use of the Service, You agree not to: (a) take any action that imposes an unreasonable load on the Service’ infrastructure, (b) use any device, software or routine to interfere or attempt to interfere with the proper working of the Service or any activity being conducted on the Service, (c) attempt to decipher, decompile, disassemble or reverse engineer any of the software comprising or making up the Service, (d) delete or alter any material posted on the Service by Antengene or any other person or entity, or (e) frame or link to any of the materials or information available on the Service. 4.3 You acknowledge and agree that any data, questions, comments, suggestions, ideas, feedback, or other information provided by You to Antengene (“ Submissions ”) will be treated as non-confidential and shall become Our sole property. We shall own exclusive rights, including all intellectual property rights, and shall be entitled to the unrestricted use and dissemination of these Submissions for any lawful purpose, commercial or otherwise, without acknowledgment or compensation to You. You hereby waive all moral rights to any such Submissions, and You hereby warrant that any such Submissions are original with You or that You have the right to submit such Submissions. You agree there shall be no recourse against Us for any alleged or actual infringement or misappropriation of any proprietary right in Your Submissions. Your Submissions might be publicly accessible. Important and private information should be protected by You. Antengene is not liable for protection of privacy of email or other information transferred through the Internet or any other network that you may use. 5. Site Management 5.1 We reserve the right, but not the obligation, to: (1) monitor the Service for violations of these Terms and Conditions; (2) take appropriate legal action against anyone who, in Our sole discretion, violates the law or these Terms and Conditions, including without limitation, reporting such user to law enforcement authorities; (3) in Our sole discretion and without limitation, notice, or liability, to remove from the Service or otherwise disable all files and content that are excessive in size or are in any way burdensome to Our systems; and (4) otherwise manage the Service in a manner designed to protect Our rights and property and to facilitate the proper functioning of the Service. 5.2 We reserve the right to change, modify, or remove the contents of the Service at any time or for any reason at Our sole discretion without notice. However, we have no obligation to update any information on Our Service. We also reserve the right to modify or discontinue all or part of the Service without notice at any time. We will not be liable to You or any third party for any modification, suspension, or discontinuance of the Service. 5.3 We cannot guarantee the Service will be available at all times. We may experience hardware, software, or other problems or need to perform maintenance related to the Service, resulting in interruptions, delays, or errors. We reserve the right to change, revise, update, suspend, discontinue, or otherwise modify the Service at any time or for any reason without notice to You. You agree that we have no liability whatsoever for any loss, damage, or inconvenience caused by Your inability to access or use the Service during any downtime or discontinuance of the Service. Nothing in these Terms and Conditions will be construed to obligate Us to maintain and support the Service or to supply any corrections, updates, or releases in connection therewith. 6. Links to Other Websites 6.1 Our Service may contain links to third-party websites or services that are not owned or controlled by Antengene. 6.2 Antengene has no control over, and assumes no responsibility for, the content, privacy policies, or practices of any third-party websites or services. You further acknowledge and agree that Antengene shall not be responsible or liable, directly or indirectly, for any damage or loss caused or alleged to be caused by or in connection with the use of or reliance on any such content, goods or services available on or through any such websites or services. 6.3 We strongly advise You to read the terms and conditions and privacy policies of any third-party websites or services that You visit. 7. Termination 7.1 We may terminate or suspend Your access immediately, without prior notice or liability, for any reason whatsoever, including without limitation if You breach these Terms and Conditions. 7.2 Upon termination, Your right to use the Service will cease immediately. 8. Limitation of Liability 8.1 Notwithstanding any damages that You might incur, the entire liability of Antengene and any of its suppliers under any provision of this Terms and Your exclusive remedy for all of the foregoing shall be limited to the amount actually paid by You through the Service or USD100 if You haven't purchased anything through the Service. 8.2 TO THE MAXIMUM EXTENT PERMITTED BY APPLICABLE LAW, IN NO EVENT SHALL ANTENGENE OR ITS SUPPLIERS BE LIABLE FOR ANY SPECIAL, INCIDENTAL, INDIRECT, OR CONSEQUENTIAL DAMAGES WHATSOEVER (INCLUDING, BUT NOT LIMITED TO, DAMAGES FOR LOSS OF PROFITS, LOSS OF DATA OR OTHER INFORMATION, FOR BUSINESS INTERRUPTION, FOR PERSONAL INJURY, LOSS OF PRIVACY ARISING OUT OF OR IN ANY WAY RELATED TO THE USE OF OR INABILITY TO USE THE SERVICE, THIRD-PARTY SOFTWARE AND/OR THIRD-PARTY HARDWARE USED WITH THE SERVICE, OR OTHERWISE IN CONNECTION WITH ANY PROVISION OF THIS TERMS), EVEN IF ANTENGENE OR ANY SUPPLIER HAS BEEN ADVISED OF THE POSSIBILITY OF SUCH DAMAGES AND EVEN IF THE REMEDY FAILS OF ITS ESSENTIAL PURPOSE. 8.3 YOU AGREE THAT ANY CAUSE OF ACTION OR CLAIM YOU MAY HAVE AGAINST ANTENGENE ARISING OUT OF OR RELATED TO THESE TERMS OR THE SERVICES OR ANY INFORMATION PROVIDED THROUGH THE SERVICES, MUST BE BROUGHT WITHIN ONE (1) YEAR AFTER THE CAUSE OF ACTION OR CLAIM ACCRUES, OR BE PERMANENTLY BARRED . 8.4 Some jurisdictions do not allow the exclusion of implied warranties or limitation of liability for incidental or consequential damages, which means that some of the above limitations may not apply. In these jurisdictions, each party's liability will be limited to the greatest extent permitted by law. 9. "AS IS" and "AS AVAILABLE" Disclaimer 9.1 THE SERVICE IS PROVIDED TO YOU "AS IS" AND "AS AVAILABLE" AND WITH ALL FAULTS AND DEFECTS WITHOUT WARRANTY OF ANY KIND. TO THE MAXIMUM EXTENT PERMITTED UNDER APPLICABLE LAW, ANTENGENE, ON ITS OWN BEHALF AND ON BEHALF OF ITS AFFILIATES AND ITS AND THEIR RESPECTIVE LICENSORS AND SERVICE PROVIDERS, EXPRESSLY DISCLAIMS ALL WARRANTIES, WHETHER EXPRESS, IMPLIED, STATUTORY OR OTHERWISE, WITH RESPECT TO THE SERVICE, INCLUDING ALL IMPLIED WARRANTIES OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE, TITLE AND NON-INFRINGEMENT, AND WARRANTIES THAT MAY ARISE OUT OF COURSE OF DEALING, COURSE OF PERFORMANCE, USAGE OR TRADE PRACTICE. WITHOUT LIMITATION TO THE FOREGOING, ANTENGENE PROVIDES NO WARRANTY OR UNDERTAKING, AND MAKES NO REPRESENTATION OF ANY KIND THAT THE SERVICE WILL MEET YOUR REQUIREMENTS, ACHIEVE ANY INTENDED RESULTS, BE COMPATIBLE OR WORK WITH ANY OTHER SOFTWARE, APPLICATIONS, SYSTEMS OR SERVICES, OPERATE WITHOUT INTERRUPTION, MEET ANY PERFORMANCE OR RELIABILITY STANDARDS OR BE ERROR FREE OR THAT ANY ERRORS OR DEFECTS CAN OR WILL BE CORRECTED. 9.2 WITHOUT LIMITING THE FOREGOING, NEITHER ANTENGENE NOR ANY OF ANTENGENE'S PROVIDER MAKES ANY REPRESENTATION OR WARRANTY OF ANY KIND, EXPRESS OR IMPLIED: (I) AS TO THE OPERATION OR AVAILABILITY OF THE SERVICE, OR THE INFORMATION, CONTENT, AND MATERIALS OR PRODUCTS INCLUDED THEREON; (II) THAT THE SERVICE WILL BE UNINTERRUPTED OR ERROR-FREE; (III) AS TO THE ACCURACY, RELIABILITY, OR CURRENCY OF ANY INFORMATION OR CONTENT PROVIDED THROUGH THE SERVICE; OR (IV) THAT THE SERVICE, ITS SERVERS, THE CONTENT, OR E-MAILS SENT FROM OR ON BEHALF OF ANTENGENE ARE FREE OF VIRUSES, SCRIPTS, TROJAN HORSES, WORMS, MALWARE, TIMEBOMBS OR OTHER HARMFUL COMPONENTS. 9.3 Some jurisdictions do not allow the exclusion of certain types of warranties or limitations on applicable statutory rights of a consumer, so some or all of the above exclusions and limitations may not apply to You. But in such a case the exclusions and limitations set forth in this section shall be applied to the greatest extent enforceable under applicable law. 10. Indemnification You agree to defend, indemnify, and hold Antengene and its Affiliates, licensors, partners, providers, and their respective successors harmless from and against any claims, actions or demands, including, without limitation, reasonable legal and accounting fees, arising or resulting from Your breach of these Terms or Your access to, use or misuse of the Service. Antengene shall provide notice to You of any such claim, suit, or proceeding. Antengene reserves the right to assume the exclusive defense and control of any matter which is subject to indemnification under this section. In such case, You agree to cooperate with any reasonable requests assisting Antengene’s defense of such matter. 11. Governing Law The laws of the State of New York, excluding its conflicts of law rules, shall govern this Terms and Your use of the Service. Your use of the Application may also be subject to other local, state, national, or international laws. 12. Disputes Resolution If You have any concern or dispute about the Service, You agree to first try to resolve the dispute informally by contacting Antengene. 13. Compliance You are solely responsible for ensuring compliance with the laws of Your specific jurisdiction. You expressly agree to comply with any applicable export restrictions under any applicable export control laws and not to export or re-export any part of the Service to countries or persons prohibited under such export control laws. By downloading any content of the Service, You are expressly agreeing that You are not in a country where such export is prohibited or are a person or entity for which such export is prohibited. 14. Translation Interpretation These Terms and Conditions may have been translated if We have made them available to You on Our Service. You agree that the original English text shall prevail in the case of a dispute. 15. Changes to These Terms and Conditions 15.1 We reserve the right, at Our sole discretion, to modify or replace these Terms at any time. If a revision is material We will make reasonable efforts to provide at least 30 days' notice prior to any new terms taking effect. What constitutes a material change will be determined at Our sole discretion. 15.2 By continuing to access or use Our Service after those revisions become effective, You agree to be bound by the revised terms. If You do not agree to the new terms, in whole or in part, please stop using the Service. 16. Miscellaneous 16.1 If any provision of these Terms is held to be unenforceable or invalid, such provision will be changed and interpreted to accomplish the objectives of such provision to the greatest extent possible under the applicable law and the remaining provisions will continue in full force and effect. 16.2 Except as provided herein, the failure to exercise a right or to require performance of an obligation under these Terms shall not affect a party's ability to exercise such right or require such performance at any time thereafter nor shall the waiver of a breach constitute a waiver of any subsequent breach. 16.3 Visiting the Service, sending Us emails, and completing online forms constitute electronic communications. You consent to receive electronic communications, and You agree that all agreements, notices, disclosures, and other communications we provide to You electronically, via email and on the Service, satisfy any legal requirement that such communication be in writing. 16.4 These Terms and Conditions and any policies or operating rules posted by Us on the Service or in respect to the Service constitute the entire agreement and understanding between You and Us. 16.5 We may assign any or all of Our rights and obligations to others at any time without notice to You. We shall not be responsible or liable for any loss, damage, delay, or failure to act caused by any cause beyond Our reasonable control. 16.6 There is no joint venture, partnership, employment or agency relationship created between You and Us as a result of these Terms and Conditions or use of the Service. 16.7 You agree that these Terms and Conditions will not be construed against Us by virtue of having drafted them. 17. Contact Us If You have any questions about these Terms and Conditions, You can contact Us: · By email: [email protected]

The release as fetched from its publisher. antengene.com ↗