First patient enrolled in pivotal study of RG6042 (IONIS-HTT Rx) for people with Huntington's Disease

First of 4+ Ionis programs expected to advance to pivotal studies this year Ionis earns $35 million milestone payment CARLSBAD, Calif., Jan. 28, 2019 /PRNewswire/ -- Ionis Pharmaceuticals, Inc. (NASDAQ: IONS), the leader in antisense therapeutics, today announced that its partner Roche, also known as Genentech in the United States, has enrolled the first patient in a pivotal study of RG6042 (IONIS-HTTRx) for people living with symptoms of Huntington's disease (HD), a hereditary neurodegenerative disorder for which there is currently no approved disease-modifying treatment. RG6042 is the first therapy in pivotal trials designed to target the underlying cause of HD by reducing production of the toxic mutant huntingtin protein (mHTT). Ionis has earned a $35 million milestone payment for the initiation of the study.

The release as fetched from its publisher. ionis.com ↗