Zydus to present PBC and NASH clinical trial data of Saroglitazar Mg at the AASLDs The Liver Meeting Digital Experience 2020

Press Release Press Release Press Release Press Release Press Release Press Release Press Release Press Re²lease Cadila Healthcare Limited Regd. Office : ‘Zydus Corporate Park’, Scheme No. 63, Survey No. 536, Khoraj (Gandhinagar), Nr. Vaishnodevi Circle, S. G. Highway, Ahmedabad 382 481, India. Phone : +91-079-71800000, +91-079-48040000 www.zyduscadila.com CIN : L24230GJ1995PLC025878 For further information please contact : The Corporate Communications Department Zydus to present PBC and NASH clinical trial data of Saroglitazar Mg at the AASLD’s The Liver Meeting Digital Experience™ 2020 Ahmedabad, India, November 2, 2020 Zydus, a leading discovery based, global pharmaceutical company today announced that a Late-Breaker Oral Presentation and two Poster Presentations on Saroglitazar Mg has been accepted for presentation at The Liver Meeting® 2020, the Annual Meeting of the American Association for the Study of Liver Diseases (AASLD), which is taking place virtually from November 13-16, 2020. Saroglitazar Mg is in various stages of clinical trials to evaluate the safety, tolerability, and efficacy in patients with Primary Biliary Cholangitis (PBC) and Non Alcoholic Steato Hepatitis (NASH). Speaking on the development, Pankaj R. Patel, Chairman, Cadila Healthcare Ltd., said, “We look forward to present the new data on Saroglitazar Mg at The Liver Meeting Digital Experience™, the Annual Meeting of the American Association for the Study of Liver Diseases (AASLD). Zydus is committed to developing novel therapies for patients living with liver diseases like PBC and NASH”. Abstract Title: “RESULTS OF PHASE 2, PROSPECTIVE, MULTICENTER, RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED STUDY TO EV ALUATE SAFETY , TOLERABILITY AND EFFICACY OF SAROGLITAZAR MAGNESIUM IN PATIENTS WITH PRIMARY BILIARY CHOLANGITIS (EPICS)” Publication Number : LO12 Session Title : Late-breaking Oral Session 2 Presentation Type : Oral presentation Session Date and Time : Monday, November 16, 2020, 2:00 PM Abstract Title: “SAROGLITAZAR, A DUAL PPAR α/γ AGONIST, RESOLVED STEATOHEPATITIS IN A RANDOMIZED DOUBLE BLINDED PLACEBO CONTROLLED PHASE 2 PROOF OF CONCEPT PILOT TRIAL” Publication Number : 1695 Session Title : NAFLD and NASH: Therapeutics - Pharmacologic and Other Presentation Type : Poster Presentation Press Release Press Release Press Release Press Release Press Release Press Release Press Release Press Re²lease Cadila Healthcare Limited Regd. Office : ‘Zydus Corporate Park’, Scheme No. 63, Survey No. 536, Khoraj (Gandhinagar), Nr. Vaishnodevi Circle, S. G. Highway, Ahmedabad 382 481, India. Phone : +91-079-71800000, +91-079-48040000 www.zyduscadila.com CIN : L24230GJ1995PLC025878 For further information please contact : The Corporate Communications Department Abstract Title: “SAROGLITAZAR ATTENUATES PRIMARY SCLEROSING CHOLANGITIS IN Mdr2−/− MICE MODEL: A COMPARISON WITH OBETICHOLIC ACID” Publication Number : 1270 Session title : Human Cholestatic and Autoimmune Liver Diseases: PBC/PSC and Other Cholestatis Diseases; Autoimmune Liver Disease Presentation Type : Poster Presentation About Primary Biliary Cholangitis (PBC) PBC is a liver disease, caused due to progressive destruction of the bile ducts in the liver which leads to reduction of bile flow – a condition referred to as cholestasis. With an increasing number of people being affected by PBC which can lead to progressive cholestasis and even turn fatal, there is a pressing need to develop therapies which help to achieve an adequate reduction in Alkaline Phosphotase (ALP) or bilirubin and bring in better tolerance and efficacy. About NASH NASH is a progressive disease of the liver, which starts with fat accumulation in the liver known as Non- Alcoholic Fatty Liver Disease (NAFLD). This condition could progress to cirrhosis and liver failure. Liver transplantation is the only option for managing advanced cirrhosis with liver failure. About Zydus Zydus Cadila is an innovative, global pharmaceutical company that discovers, develops, manufactures and markets a broad range of healthcare therapies, including small molecule drugs, biologic therapeutics and vaccines. The group employs nearly 25,000 people worldwide, including 1,400 scientists engaged in R & D, and is dedicated to creating healthier communities globally. www.zyduscadila.com ***

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