Polyoxidonium® added to updated Temporary Anti-COVID-19 Guidelines of the Russian Ministry of Health

The original drug Polyoxidonium ® (azoximer bromide) has been added to the updated Temporary Anti-COVID-19 Guidelines of the Russian Ministry of Health for the prevention, diagnosis and treatment of the novel coronavirus infection. According to the document, azoximer bromide is indicated for non-specific drug prevention of COVID-19. In the fall of 2023, Russian authorities record a significant increase in COVID-19 incidence again, with the number of detected cases having increased by 15% over the past week, as reported by the Federal Response Center [ 1 ] . On October 26, 2023, the Ministry of Health approved revised temporary Anti-COVID-19 Guidelines No. 18 by adding Polyoxidonium ® thereto. The Russian drug developed by Petrovax Pharm was added to the document upon successful data from the meta-analysis titled “Experience of Using Azoximer Bromide for the Prevention of Acute Respiratory Infections and COVID-19 in Adults in High-Risk Groups (Red Zone Medical Workers)”, which covered 1,141 participants aged 18 to 69 years [ 2 ] . Doctors in the red zone who received Polyoxidonium ® as prevention therapy showed greater resistance to infection, and COVID-19 was diagnosed in them 3 times less often than in the control group. The study also noted a favorable tolerability profile for the drug. The main indications of Polyoxidonium are the prevention and treatment of acute respiratory viral infections and influenza in adults and children aged 3 years or older [ 3 ] . Clinical trials of the drug for the prevention and treatment of COVID-19 began at the peak of the pandemic in 2020. In the same year, Slovakia included it in its [ 4 ] COVID-19 treatment recommendations. The drug is also added to the FMBA Guidelines [ 5 ] for the prevention and treatment of influenza and other acute respiratory viral infections during the COVID-19 pandemic, in addition to the Flu in Adults clinical recommendations of the Russian Ministry of Health [ 6 ] . Polyoxidonium ® is also on the list of Vital and Essential Drugs and is widely used in Russia and abroad, including the EU. #COVID #Recommendations #Ministry of Health #Polyoxidonium 1 https://xn—80aesfpebagmfblc0a.xn—p1ai/information/ 2 https://www.rmj.ru/articles/infektsionnye_bolezni/opyt-primeneniya-azoksimera-bromida-dlya-profilaktiki-ostrykh-respiratornykh-zabolevaniy-i-covid-19-u-vzroslykh-iz-gruppy-povyshennogo-riska-infitsirovaniya-meditsinskikh-rabotnikov-krasnoy-zony-metaanaliz-kontroliruemykh-klinicheskikh-issledovaniy/ 3 Dosage form: tablets 4 https://www.health.gov.sk/Clanok?Hlavna-sprava-COVID-19 5 https://www.garant.ru/products/ipo/prime/doc/405623221/ 6 https://cr.minzdrav.gov.ru/recomend/749_1

The release as fetched from its publisher. petrovax.com ↗