Clover initiates GLP studies on SCB-313 (Trail-Trimer) at National Shanghai Center for New Drug Safety Evaluation and Research.
2016-02-19 · Clover Biopharmaceuticals AUS Pty · original cloverbiopharma.com ↗
Clover initiates GLP studies on SCB-313 (Trail-Trimer) at National Shanghai Center for New Drug Safety Evaluation and Research. CHENGDU, CHINA, February 19, 2016 — Clover initiated GLP studies on its leading anti-cancer trimeric biologic, SCB-313 (Trail-Trimer) at National Shanghai Center for New Drug Safety Evaluation and Research. Funded by multiple grants from the central government and designed with the patented Trimer-Tag technology, SCB-313 is a first-in-class, disulfide bond-linked trimeric Trail (Apo2L) produced from CHO cells. Unliked the bacterially produced ligand, SCB-313 is highly stable and glycosylated homo-trimer with more favorable PK and PD profiles.
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