Drug Treatment for Alcoholics With Bipolar Disorder

Phase 2 Completed 72 enrolled National Institute on Alcohol Abuse and Alcoholism (NIAAA) University of Pittsburgh · collab

RandomizedParallel-groupQuadruple-blindTreatment

Summary

The purpose of this study is to test the effectiveness of sodium valproate (Depacon) in treating individuals with alcohol dependence and comorbid bipolar disorder.

Timeline

Start: 2000-10
Primary completion: 2003-08
Completion: 2003-08

Publications

Results Salloum IM, Cornelius JR, Daley DC, Kirisci L, Himmelhoch JM, Thase ME. Efficacy of valproate maintenance in patients with bipolar disorder and alcoholism: a double-blind placebo-controlled study. Arch Gen Psychiatry. 2005 Jan;62(1):37-45. doi: 10.1001/archpsyc.62.1.37.

Drugs

Evaluation	Drug	Modality	Dose	Route
Comparator	Valproate	Small molecule	—	—

Drug Treatment for Alcoholics With Bipolar Disorder

Summary

Timeline

Publications

Drugs

Indications