drugset / Trial / NCT00000451
Drug Therapy for Alcohol Dependence in Alaska Natives (Naltrexone/Sertraline)
Phase 2
Completed
198 enrolled
Yale University
National Institute on Alcohol Abuse and Alcoholism (NIAAA) · collab
RandomizedParallel-groupTriple-blindTreatment
Summary
This study will assess the ability of naltrexone (Revia) to reduce the risk of relapse in Alaska natives with alcohol dependence. The study will also examine whether a combination of naltrexone and sertraline (Zoloft) yields better abstinence rates than naltrexone used alone. Alaska Native individuals will be recruited into a 16 week outpatient study.
Timeline
- Start
- 2003-01
- Primary completion
- 2005-08
- Completion
- 2005-11
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Naltrexone | Small molecule | — | — |
| Subject | Sertraline | Small molecule | — | — |