Evaluation of Subcutaneous Desferrioxamine as Treatment for Transfusional Hemochromatosis

Summary

To determine whether deferoxamine prevented the complications of transfusional iron overload.

Timeline

Start

1978-01

Primary completion

—

Completion

1994-09

Publications

• Background Nienhuis AW, Griffith P, Strawczynski H, Henry W, Borer J, Leon M, Anderson WF. Evaluation of cardiac function in patients with thalassemia major. Ann N Y Acad Sci. 1980;344:384-96. doi: 10.1111/j.1749-6632.1980.tb33677.x.
• Background Brittenham GM, Griffith PM, Nienhuis AW, McLaren CE, Young NS, Tucker EE, Allen CJ, Farrell DE, Harris JW. Efficacy of deferoxamine in preventing complications of iron overload in patients with thalassemia major. N Engl J Med. 1994 Sep 1;331(9):567-73. doi: 10.1056/NEJM199409013310902.

Drugs

Indications